A multicenter randomized controlled trial for bright light therapy in adults with intellectual disabilities and depression: Study protocol and obstacle management

Pauline Hamers, Heleen M Evenhuis, Heidi Hermans

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Due to the limited cognitive and communicative abilities of adults with intellectual disabilities (ID), current treatment options for depression are often limited to lifestyle changes and pharmacological treatment. Bright light therapy (BLT) is an effective intervention for both seasonal and non-seasonal depression in the general population. BLT is an inexpensive, easy to carry out intervention with minimal side effects. However, knowledge on its anti-depressant effect in adults with ID is lacking. Obstacles in realizing a controlled intervention study in this particular study population may have contributed to this lack. To study the effect of BLT on depression in this population, it is necessary to successfully execute a multicenter randomized controlled trial (RCT). Therefore, the study protocol and the management of anticipated obstacles regarding this trial are presented.

Original languageEnglish
Pages (from-to)96-106
Number of pages11
JournalResearch in Developmental Disabilities
Volume60
DOIs
Publication statusPublished - Jan 2017
Externally publishedYes

Keywords

  • Actigraphy
  • Adult
  • Circadian Rhythm
  • Depression/metabolism
  • Depressive Disorder, Major/metabolism
  • Hair/chemistry
  • Humans
  • Hydrocortisone/analysis
  • Intellectual Disability/psychology
  • Melatonin/analysis
  • Phototherapy/methods
  • Saliva/chemistry
  • Stress, Psychological/metabolism

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