An assisted structured reflection on life events and life goals in advanced cancer patients: Outcomes of a randomized controlled trial (Life InSight Application (LISA) study)

Renske Kruizinga, Michael Scherer-Rath, Johannes Bam Schilderman, Iris D Hartog, Jacoba Pm Van Der Loos, Hantie P Kotzé, Anneke M Westermann, Heinz-Josef Klümpen, Francesco Kortekaas, Cecile Grootscholten, Frans Bossink, Jolanda Schrama, Willem Van De Vrande, Natascha Awp Schrama, Willem Blokland, Filip Yfl De Vos, Annemieke Kuin, Wim G Meijer, Martijn Gh Van Oijen, Mirjam Ag SprangersHanneke Wm Van Laarhoven

Research output: Contribution to journalArticleScientificpeer-review

Abstract

BACKGROUND:: Diagnosis and treatment of incurable cancer as a life-changing experience evokes difficult existential questions.

AIM:: A structured reflection could improve patients' quality of life and spiritual well-being. We developed an interview model on life events and ultimate life goals and performed a randomized controlled trial to evaluate the effect thereof on quality of life and spiritual well-being.

DESIGN:: The intervention group had two consultations with a spiritual counselor. The control group received care as usual. EORTC QLQ-C15-PAL and the FACIT-sp were administered at baseline and 2 and 4 months after baseline. Linear mixed model analysis was performed to test between-group differences over time.

PARTICIPANTS:: Adult patients with incurable cancer and a life expectancy ⩾6 months were randomized in a 1:1 ratio to the intervention or control group.

RESULTS:: A total of 153 patients from six different hospitals were included: 77 in the intervention group and 76 in the control group. Quality of life and spiritual well-being did not significantly change over time between groups. The experience of Meaning/Peace was found to significantly influence quality of life ( β = 0.52, adj. R2 = 0.26) and satisfaction with life ( β = 0.61, adj. R2 = 0.37).

CONCLUSION:: Although our newly developed interview model was well perceived by patients, we were not able to demonstrate a significant difference in quality of life and spiritual well-being between groups. Future interventions by spiritual counselors aimed at improving quality of life, and spiritual well-being should focus on the provision of sources of meaning and peace.

Original languageEnglish
Pages (from-to)221-231
Number of pages11
JournalPalliative Medicine
Volume33
Issue number2
DOIs
Publication statusPublished - Feb 2019

Keywords

  • ANXIETY
  • CONTINGENCY
  • DEPRESSION
  • EXPERIENCE
  • NETHERLANDS
  • Oncology
  • PALLIATIVE CARE
  • QUALITY-OF-LIFE
  • RELIGION
  • SPIRITUAL CARE
  • SUPPORTIVE CARE
  • palliative care
  • randomized controlled trials
  • spiritual care
  • spiritual care givers
  • spirituality

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