Cancer or no cancer

The influence of trait anxiety and diagnosis on quality of life with breast cancer and benign disease: A prospective, longitudinal study

C.M.G. Keyzer-Dekker, J. de Vries, M.C. Mertens, J.A. Roukema, A.F.W. van der Steeg

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background
High trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis.
Methods
In a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months.
Results
At 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL.
Conclusions
The course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.
Original languageEnglish
Pages (from-to)2140-2147
JournalWorld journal of surgery: Official journal of the International Society of Surgery = Société Internationale de Chirurgie
Volume37
Issue number9
DOIs
Publication statusPublished - 2013

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Neoplasms
Gallstones
Laparoscopic Cholecystectomy
Linear Models

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@article{46d151a58697429f944c19d3e080a5ec,
title = "Cancer or no cancer: The influence of trait anxiety and diagnosis on quality of life with breast cancer and benign disease: A prospective, longitudinal study",
abstract = "BackgroundHigh trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis.MethodsIn a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months.ResultsAt 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL.ConclusionsThe course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.",
author = "C.M.G. Keyzer-Dekker and {de Vries}, J. and M.C. Mertens and J.A. Roukema and {van der Steeg}, A.F.W.",
year = "2013",
doi = "10.1007/s00268-013-2088-4",
language = "English",
volume = "37",
pages = "2140--2147",
journal = "World journal of surgery: Official journal of the International Society of Surgery = Soci{\'e}t{\'e} Internationale de Chirurgie",
issn = "0364-2313",
publisher = "Springer New York",
number = "9",

}

TY - JOUR

T1 - Cancer or no cancer

T2 - The influence of trait anxiety and diagnosis on quality of life with breast cancer and benign disease: A prospective, longitudinal study

AU - Keyzer-Dekker, C.M.G.

AU - de Vries, J.

AU - Mertens, M.C.

AU - Roukema, J.A.

AU - van der Steeg, A.F.W.

PY - 2013

Y1 - 2013

N2 - BackgroundHigh trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis.MethodsIn a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months.ResultsAt 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL.ConclusionsThe course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.

AB - BackgroundHigh trait anxiety (HTA) causes an impaired quality of life (QOL) and fatigue in women with breast cancer (BC) and benign breast disease (BBD). We examined whether the lowered QOL was determined solely by the personality characteristic HTA or by the combination of personality and diagnosis.MethodsIn a prospective longitudinal study, women with BC (n = 152), BBD (n = 205), or gallstone disease (GD) before laparoscopic cholecystectomy (n = 128) were included. Questionnaires concerning trait anxiety (baseline), fatigue, and QOL were completed at baseline and at 6 months. Multivariate linear regression analysis was performed to analyze the predictors for QOL at 6 months.ResultsAt 6 months QOL scores were increased in the GD group, especially in women without HTA. For women without HTA, in the BBD group the scores for fatigue and physical QOL had improved at 6 months, whereas in the BC group physical QOL and fatigue was impaired. Women with HTA scored unfavorably on fatigue and QOL. HTA was the most important factor influencing QOL.ConclusionsThe course of QOL and fatigue during follow-up were significantly different for each diagnosis. Particularly HTA had a negative impact on QOL and fatigue. Especially the combination HTA and BC caused impaired QOL and fatigue. We recommend identifying women with BC and HTA and offer them a tailor-made follow-up protocol.

U2 - 10.1007/s00268-013-2088-4

DO - 10.1007/s00268-013-2088-4

M3 - Article

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JO - World journal of surgery: Official journal of the International Society of Surgery = Société Internationale de Chirurgie

JF - World journal of surgery: Official journal of the International Society of Surgery = Société Internationale de Chirurgie

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