Cardiac reactivity and stimulant use in adolescents with autism spectrum disorders with comorbid ADHD versus ADHD

M. Bink, A. Popma, I.L. Bongers, G.J.M. van Boxtel, A. Denissen, Ch. van Nieuwenhuizen

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)

Abstract

A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56 %) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD.
Keywords: Cardiac adaptation, HRV, ASD, ADHD, Stimulant medication
Original languageEnglish
Pages (from-to)481-494
JournalJournal of Autism and Developmental Disorders
Volume45
Issue number2
DOIs
Publication statusPublished - 2015

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