Cognitive deficits in meningioma patients in preoperative and postoperative stage

Research output: Contribution to journalMeeting AbstractOther research output

Abstract

Objective: 
Cognitive dysfunction is common in patients with primarybrain tumors and it is now recognized as an independent prognostic factorin survival. In addition, cognitive functioning has a major impacton quality of life and the ability to perform activities of daily living. Previousstudies have mainly focused on glioma patients. This prospectivefollow-up study focuses on cognitive functioning in meningioma patientsbefore and after surgery.
Participants and Methods: 
Sixty-one meningioma patients, who underwentan intracranial neurosurgical procedure in the St. ElisabethHospital, were assessed one day before surgery and 3 months after surgery.To identify the impaired domains of cognitive function, all patientswere assessed with a computerized neuropsychological test, CNS VitalSigns. The standard scores of the patients on seven cognitive domainswere compared with the normative healthy American control group fromCNS VS by means of one-tailed one-sample t-tests.
Results: 
Meningioma patients showed significantly lower scores on allcognitive domains preoperatively, in comparison with healthy controls(p < 0.05). After surgery, the performance of the patients was significantlylower on the domains of memory, psychomotor speed, reactiontime and complex attention. Their scores on the three other domains(cognitive flexibility, processing speed and executive functioning) didnot deviate from the controls.
Conclusions: 
Based on these results, we can conclude that meningiomapatients are faced with substantial cognitive dysfunction in several cognitivedomains both pre- and postoperatively. This study emphasizesthe importance of the use of neuropsychological tests to identify cognitivedeficits in meningioma patients, so that appropriate treatment canbe provided.
Original languageEnglish
Pages (from-to)109-109
JournalJINS. Journal of the International Neuropsychological Society
Volume19
Issue numberS2
DOIs
Publication statusPublished - Aug 2013

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Meningioma
Ambulatory Surgical Procedures
Glioma
Neoplasms

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@article{3575ae8c29ae47758287040bf3e3fc1b,
title = "Cognitive deficits in meningioma patients in preoperative and postoperative stage",
abstract = "Objective: Cognitive dysfunction is common in patients with primarybrain tumors and it is now recognized as an independent prognostic factorin survival. In addition, cognitive functioning has a major impacton quality of life and the ability to perform activities of daily living. Previousstudies have mainly focused on glioma patients. This prospectivefollow-up study focuses on cognitive functioning in meningioma patientsbefore and after surgery.Participants and Methods: Sixty-one meningioma patients, who underwentan intracranial neurosurgical procedure in the St. ElisabethHospital, were assessed one day before surgery and 3 months after surgery.To identify the impaired domains of cognitive function, all patientswere assessed with a computerized neuropsychological test, CNS VitalSigns. The standard scores of the patients on seven cognitive domainswere compared with the normative healthy American control group fromCNS VS by means of one-tailed one-sample t-tests.Results: Meningioma patients showed significantly lower scores on allcognitive domains preoperatively, in comparison with healthy controls(p < 0.05). After surgery, the performance of the patients was significantlylower on the domains of memory, psychomotor speed, reactiontime and complex attention. Their scores on the three other domains(cognitive flexibility, processing speed and executive functioning) didnot deviate from the controls.Conclusions: Based on these results, we can conclude that meningiomapatients are faced with substantial cognitive dysfunction in several cognitivedomains both pre- and postoperatively. This study emphasizesthe importance of the use of neuropsychological tests to identify cognitivedeficits in meningioma patients, so that appropriate treatment canbe provided.",
author = "{van der Linden}, S.D. and I. Meskal and M.E. Salden and G.J.M. Rutten and M.M. Sitskoorn",
year = "2013",
month = "8",
doi = "10.1017/S1355617713001033",
language = "English",
volume = "19",
pages = "109--109",
journal = "JINS. Journal of the International Neuropsychological Society",
issn = "1355-6177",
publisher = "Cambridge University Press",
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}

Cognitive deficits in meningioma patients in preoperative and postoperative stage. / van der Linden, S.D.; Meskal, I.; Salden, M.E.; Rutten, G.J.M.; Sitskoorn, M.M.

In: JINS. Journal of the International Neuropsychological Society, Vol. 19, No. S2, 08.2013, p. 109-109.

Research output: Contribution to journalMeeting AbstractOther research output

TY - JOUR

T1 - Cognitive deficits in meningioma patients in preoperative and postoperative stage

AU - van der Linden, S.D.

AU - Meskal, I.

AU - Salden, M.E.

AU - Rutten, G.J.M.

AU - Sitskoorn, M.M.

PY - 2013/8

Y1 - 2013/8

N2 - Objective: Cognitive dysfunction is common in patients with primarybrain tumors and it is now recognized as an independent prognostic factorin survival. In addition, cognitive functioning has a major impacton quality of life and the ability to perform activities of daily living. Previousstudies have mainly focused on glioma patients. This prospectivefollow-up study focuses on cognitive functioning in meningioma patientsbefore and after surgery.Participants and Methods: Sixty-one meningioma patients, who underwentan intracranial neurosurgical procedure in the St. ElisabethHospital, were assessed one day before surgery and 3 months after surgery.To identify the impaired domains of cognitive function, all patientswere assessed with a computerized neuropsychological test, CNS VitalSigns. The standard scores of the patients on seven cognitive domainswere compared with the normative healthy American control group fromCNS VS by means of one-tailed one-sample t-tests.Results: Meningioma patients showed significantly lower scores on allcognitive domains preoperatively, in comparison with healthy controls(p < 0.05). After surgery, the performance of the patients was significantlylower on the domains of memory, psychomotor speed, reactiontime and complex attention. Their scores on the three other domains(cognitive flexibility, processing speed and executive functioning) didnot deviate from the controls.Conclusions: Based on these results, we can conclude that meningiomapatients are faced with substantial cognitive dysfunction in several cognitivedomains both pre- and postoperatively. This study emphasizesthe importance of the use of neuropsychological tests to identify cognitivedeficits in meningioma patients, so that appropriate treatment canbe provided.

AB - Objective: Cognitive dysfunction is common in patients with primarybrain tumors and it is now recognized as an independent prognostic factorin survival. In addition, cognitive functioning has a major impacton quality of life and the ability to perform activities of daily living. Previousstudies have mainly focused on glioma patients. This prospectivefollow-up study focuses on cognitive functioning in meningioma patientsbefore and after surgery.Participants and Methods: Sixty-one meningioma patients, who underwentan intracranial neurosurgical procedure in the St. ElisabethHospital, were assessed one day before surgery and 3 months after surgery.To identify the impaired domains of cognitive function, all patientswere assessed with a computerized neuropsychological test, CNS VitalSigns. The standard scores of the patients on seven cognitive domainswere compared with the normative healthy American control group fromCNS VS by means of one-tailed one-sample t-tests.Results: Meningioma patients showed significantly lower scores on allcognitive domains preoperatively, in comparison with healthy controls(p < 0.05). After surgery, the performance of the patients was significantlylower on the domains of memory, psychomotor speed, reactiontime and complex attention. Their scores on the three other domains(cognitive flexibility, processing speed and executive functioning) didnot deviate from the controls.Conclusions: Based on these results, we can conclude that meningiomapatients are faced with substantial cognitive dysfunction in several cognitivedomains both pre- and postoperatively. This study emphasizesthe importance of the use of neuropsychological tests to identify cognitivedeficits in meningioma patients, so that appropriate treatment canbe provided.

U2 - 10.1017/S1355617713001033

DO - 10.1017/S1355617713001033

M3 - Meeting Abstract

VL - 19

SP - 109

EP - 109

JO - JINS. Journal of the International Neuropsychological Society

JF - JINS. Journal of the International Neuropsychological Society

SN - 1355-6177

IS - S2

ER -