Depressive symptoms in patients with an implantable cardioverter defibrillator

Does treatment expectations play a role?

S.S. Pedersen, Christina M Andersen, J. Denollet, M. Habibovic

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Objective: 

Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12months post implant.

Methods: 

First-time implant patients from the WEBCARE study (n=177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12months.

Results: 

Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β=0.202; p=0.020) and baseline depression (β=0.376; p<0.0001). Model 2: Baseline depression (β=0.350; p<0.0001) and Type D personality (β=0.162; p=0.042); negative treatment expectations was borderline significant (β=0.169; p=0.051). Model 3: Baseline depression (β=0.353; p<0.0001) and negative treatment expectations (β=0.180; p=0.043); Type D personality was not significant (β=0.150; p=0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively.

Conclusion: 

Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

Original languageEnglish
Pages (from-to)10-14
JournalGeneral Hospital Psychiatry: Psychiatry, Medicine and Primary Care
Volume51
DOIs
Publication statusPublished - 2018

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Implantable Defibrillators
Depression
Linear Models

Keywords

  • Aged
  • Comorbidity
  • Defibrillators, Implantable/statistics & numerical data
  • Depression/epidemiology
  • Female
  • Follow-Up Studies
  • Heart Diseases/epidemiology
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment (Health Care)/statistics & numerical data
  • Patient Satisfaction/statistics & numerical data
  • Type D Personality

Cite this

@article{75e2cd84afb342f6b8a309263ee8f392,
title = "Depressive symptoms in patients with an implantable cardioverter defibrillator: Does treatment expectations play a role?",
abstract = "Objective: Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12months post implant.Methods: First-time implant patients from the WEBCARE study (n=177; 83.1{\%} men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12months.Results: Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β=0.202; p=0.020) and baseline depression (β=0.376; p<0.0001). Model 2: Baseline depression (β=0.350; p<0.0001) and Type D personality (β=0.162; p=0.042); negative treatment expectations was borderline significant (β=0.169; p=0.051). Model 3: Baseline depression (β=0.353; p<0.0001) and negative treatment expectations (β=0.180; p=0.043); Type D personality was not significant (β=0.150; p=0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2{\%}, 24.1{\%}, and 23.3{\%} of the variance in 12-months depressive symptoms, respectively.Conclusion: Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.",
keywords = "Aged, Comorbidity, Defibrillators, Implantable/statistics & numerical data, Depression/epidemiology, Female, Follow-Up Studies, Heart Diseases/epidemiology, Humans, Male, Middle Aged, Outcome Assessment (Health Care)/statistics & numerical data, Patient Satisfaction/statistics & numerical data, Type D Personality",
author = "S.S. Pedersen and Andersen, {Christina M} and J. Denollet and M. Habibovic",
note = "Copyright {\circledC} 2017 Elsevier Inc. All rights reserved.",
year = "2018",
doi = "10.1016/j.genhosppsych.2017.12.002",
language = "English",
volume = "51",
pages = "10--14",
journal = "General Hospital Psychiatry: Psychiatry, Medicine and Primary Care",
issn = "0163-8343",
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}

Depressive symptoms in patients with an implantable cardioverter defibrillator : Does treatment expectations play a role? / Pedersen, S.S.; Andersen, Christina M; Denollet, J.; Habibovic, M.

In: General Hospital Psychiatry: Psychiatry, Medicine and Primary Care, Vol. 51, 2018, p. 10-14.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Depressive symptoms in patients with an implantable cardioverter defibrillator

T2 - Does treatment expectations play a role?

AU - Pedersen, S.S.

AU - Andersen, Christina M

AU - Denollet, J.

AU - Habibovic, M.

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2018

Y1 - 2018

N2 - Objective: Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12months post implant.Methods: First-time implant patients from the WEBCARE study (n=177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12months.Results: Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β=0.202; p=0.020) and baseline depression (β=0.376; p<0.0001). Model 2: Baseline depression (β=0.350; p<0.0001) and Type D personality (β=0.162; p=0.042); negative treatment expectations was borderline significant (β=0.169; p=0.051). Model 3: Baseline depression (β=0.353; p<0.0001) and negative treatment expectations (β=0.180; p=0.043); Type D personality was not significant (β=0.150; p=0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively.Conclusion: Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

AB - Objective: Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12months post implant.Methods: First-time implant patients from the WEBCARE study (n=177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12months.Results: Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β=0.202; p=0.020) and baseline depression (β=0.376; p<0.0001). Model 2: Baseline depression (β=0.350; p<0.0001) and Type D personality (β=0.162; p=0.042); negative treatment expectations was borderline significant (β=0.169; p=0.051). Model 3: Baseline depression (β=0.353; p<0.0001) and negative treatment expectations (β=0.180; p=0.043); Type D personality was not significant (β=0.150; p=0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively.Conclusion: Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

KW - Aged

KW - Comorbidity

KW - Defibrillators, Implantable/statistics & numerical data

KW - Depression/epidemiology

KW - Female

KW - Follow-Up Studies

KW - Heart Diseases/epidemiology

KW - Humans

KW - Male

KW - Middle Aged

KW - Outcome Assessment (Health Care)/statistics & numerical data

KW - Patient Satisfaction/statistics & numerical data

KW - Type D Personality

U2 - 10.1016/j.genhosppsych.2017.12.002

DO - 10.1016/j.genhosppsych.2017.12.002

M3 - Article

VL - 51

SP - 10

EP - 14

JO - General Hospital Psychiatry: Psychiatry, Medicine and Primary Care

JF - General Hospital Psychiatry: Psychiatry, Medicine and Primary Care

SN - 0163-8343

ER -