Emotional distress, positive affect, and mortality in patients with an implantable cardioverter defibrillator

K.C. van den Broek, F.B. Tekle, M. Habibovic, M. Alings, P.H. van der Voort, J. Denollet

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Abstract

Background
Little is known about the relationship between emotional distress and mortality in patients with an implantable cardioverter defibrillator (ICD). Our aim was to examine the predictive value of general negative and positive affect, and depressive symptoms (including its components somatic symptoms and cognitive-affective symptoms) for mortality.
Methods
ICD patients (N = 591, 81% male, mean age = 62.7 ± 10.1 years) completed the Global Mood Scale to measure the independent dimensions negative and positive mood, and the Beck Depression Inventory to measure depressive symptoms. Covariates consisted of demographic and clinical variables.
Results
During the median follow-up of 3.2 years, 96 (16.2%) patients died. After controlling for covariates, negative affect was significantly related to all-cause mortality (HR = 1.034, p = 0.002), whereas positive affect was not (HR = 1.007, p = 0.61). Depressive symptoms were also independently associated with an increased mortality risk (HR = 1.031, p = 0.030) and somatic symptoms of depression in particular (HR = 1.130, p = 0.003), but cognitive-affective symptoms were not associated with mortality (HR = 0.968, p = 0.29). When entering both significant psychological predictors in a covariate-adjusted model, negative mood remained significant (HR = 1.039, p = 0.009), but somatic symptoms of depression did not (HR = 0.988, p = 0.78). Similar results were found for cardiac-related death. Of covariates, increased age, CRT, appropriate shocks were positively related to death.
Conclusions
Negative affect in general was related to mortality, but reduced positive affect was not. Depression, particularly its somatic symptoms, was also related to mortality, while cognitive-affective symptoms were not. Future research may further focus on the differential predictive value of emotional distress factors, as well as on mechanisms that relate emotional distress factors to mortality.
Keywords: Implantable cardioverter defibrillator, Mortality, Negative mood, Positive mood, Depression
Original languageEnglish
Pages (from-to)327-332
JournalInternational Journal of Cardiology
Volume165
Issue number2
DOIs
Publication statusPublished - 2013

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Implantable Defibrillators
Depression
Affective Symptoms
Equipment and Supplies
Medically Unexplained Symptoms

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@article{8b41ce0ad07644b9953173b3b936d36b,
title = "Emotional distress, positive affect, and mortality in patients with an implantable cardioverter defibrillator",
abstract = "BackgroundLittle is known about the relationship between emotional distress and mortality in patients with an implantable cardioverter defibrillator (ICD). Our aim was to examine the predictive value of general negative and positive affect, and depressive symptoms (including its components somatic symptoms and cognitive-affective symptoms) for mortality.MethodsICD patients (N = 591, 81{\%} male, mean age = 62.7 ± 10.1 years) completed the Global Mood Scale to measure the independent dimensions negative and positive mood, and the Beck Depression Inventory to measure depressive symptoms. Covariates consisted of demographic and clinical variables.ResultsDuring the median follow-up of 3.2 years, 96 (16.2{\%}) patients died. After controlling for covariates, negative affect was significantly related to all-cause mortality (HR = 1.034, p = 0.002), whereas positive affect was not (HR = 1.007, p = 0.61). Depressive symptoms were also independently associated with an increased mortality risk (HR = 1.031, p = 0.030) and somatic symptoms of depression in particular (HR = 1.130, p = 0.003), but cognitive-affective symptoms were not associated with mortality (HR = 0.968, p = 0.29). When entering both significant psychological predictors in a covariate-adjusted model, negative mood remained significant (HR = 1.039, p = 0.009), but somatic symptoms of depression did not (HR = 0.988, p = 0.78). Similar results were found for cardiac-related death. Of covariates, increased age, CRT, appropriate shocks were positively related to death.ConclusionsNegative affect in general was related to mortality, but reduced positive affect was not. Depression, particularly its somatic symptoms, was also related to mortality, while cognitive-affective symptoms were not. Future research may further focus on the differential predictive value of emotional distress factors, as well as on mechanisms that relate emotional distress factors to mortality.Keywords: Implantable cardioverter defibrillator, Mortality, Negative mood, Positive mood, Depression",
author = "{van den Broek}, K.C. and F.B. Tekle and M. Habibovic and M. Alings and {van der Voort}, P.H. and J. Denollet",
year = "2013",
doi = "10.1016/j.ijcard.2011.08.071",
language = "English",
volume = "165",
pages = "327--332",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

Emotional distress, positive affect, and mortality in patients with an implantable cardioverter defibrillator. / van den Broek, K.C.; Tekle, F.B.; Habibovic, M.; Alings, M.; van der Voort, P.H.; Denollet, J.

In: International Journal of Cardiology, Vol. 165, No. 2, 2013, p. 327-332.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Emotional distress, positive affect, and mortality in patients with an implantable cardioverter defibrillator

AU - van den Broek, K.C.

AU - Tekle, F.B.

AU - Habibovic, M.

AU - Alings, M.

AU - van der Voort, P.H.

AU - Denollet, J.

PY - 2013

Y1 - 2013

N2 - BackgroundLittle is known about the relationship between emotional distress and mortality in patients with an implantable cardioverter defibrillator (ICD). Our aim was to examine the predictive value of general negative and positive affect, and depressive symptoms (including its components somatic symptoms and cognitive-affective symptoms) for mortality.MethodsICD patients (N = 591, 81% male, mean age = 62.7 ± 10.1 years) completed the Global Mood Scale to measure the independent dimensions negative and positive mood, and the Beck Depression Inventory to measure depressive symptoms. Covariates consisted of demographic and clinical variables.ResultsDuring the median follow-up of 3.2 years, 96 (16.2%) patients died. After controlling for covariates, negative affect was significantly related to all-cause mortality (HR = 1.034, p = 0.002), whereas positive affect was not (HR = 1.007, p = 0.61). Depressive symptoms were also independently associated with an increased mortality risk (HR = 1.031, p = 0.030) and somatic symptoms of depression in particular (HR = 1.130, p = 0.003), but cognitive-affective symptoms were not associated with mortality (HR = 0.968, p = 0.29). When entering both significant psychological predictors in a covariate-adjusted model, negative mood remained significant (HR = 1.039, p = 0.009), but somatic symptoms of depression did not (HR = 0.988, p = 0.78). Similar results were found for cardiac-related death. Of covariates, increased age, CRT, appropriate shocks were positively related to death.ConclusionsNegative affect in general was related to mortality, but reduced positive affect was not. Depression, particularly its somatic symptoms, was also related to mortality, while cognitive-affective symptoms were not. Future research may further focus on the differential predictive value of emotional distress factors, as well as on mechanisms that relate emotional distress factors to mortality.Keywords: Implantable cardioverter defibrillator, Mortality, Negative mood, Positive mood, Depression

AB - BackgroundLittle is known about the relationship between emotional distress and mortality in patients with an implantable cardioverter defibrillator (ICD). Our aim was to examine the predictive value of general negative and positive affect, and depressive symptoms (including its components somatic symptoms and cognitive-affective symptoms) for mortality.MethodsICD patients (N = 591, 81% male, mean age = 62.7 ± 10.1 years) completed the Global Mood Scale to measure the independent dimensions negative and positive mood, and the Beck Depression Inventory to measure depressive symptoms. Covariates consisted of demographic and clinical variables.ResultsDuring the median follow-up of 3.2 years, 96 (16.2%) patients died. After controlling for covariates, negative affect was significantly related to all-cause mortality (HR = 1.034, p = 0.002), whereas positive affect was not (HR = 1.007, p = 0.61). Depressive symptoms were also independently associated with an increased mortality risk (HR = 1.031, p = 0.030) and somatic symptoms of depression in particular (HR = 1.130, p = 0.003), but cognitive-affective symptoms were not associated with mortality (HR = 0.968, p = 0.29). When entering both significant psychological predictors in a covariate-adjusted model, negative mood remained significant (HR = 1.039, p = 0.009), but somatic symptoms of depression did not (HR = 0.988, p = 0.78). Similar results were found for cardiac-related death. Of covariates, increased age, CRT, appropriate shocks were positively related to death.ConclusionsNegative affect in general was related to mortality, but reduced positive affect was not. Depression, particularly its somatic symptoms, was also related to mortality, while cognitive-affective symptoms were not. Future research may further focus on the differential predictive value of emotional distress factors, as well as on mechanisms that relate emotional distress factors to mortality.Keywords: Implantable cardioverter defibrillator, Mortality, Negative mood, Positive mood, Depression

U2 - 10.1016/j.ijcard.2011.08.071

DO - 10.1016/j.ijcard.2011.08.071

M3 - Article

VL - 165

SP - 327

EP - 332

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 2

ER -