Everyday cognitive failure and depressive symptoms predict fatigue in sarcoidosis

A prospective follow-up study

Celine Hendriks, Marjolein Drent, Willemien De Kleijn, Marjon Elfferich, Petal Wijnen, J. de Vries

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Bachground:
Fatigue is a major and disabling problem in sarcoidosis. Knowledge concerning correlates of the development of fatigue and possible interrelationships is lacking.
Objective:
A conceptual model of fatigue was developed and tested.
Methods:
Sarcoidosis outpatients (n = 292) of Maastricht University Medical Center completed questionnaires regarding trait anxiety, depressive symptoms, cognitive failure, dyspnea, social support, and small fiber neuropathy (SFN) at baseline. Fatigue was assessed at 6 and 12 months. Sex, age, and time since diagnosis were taken from medical records. Pathways were estimated by means of path analyses in AMOS.
Results:
Everyday cognitive failure, depressive symptoms, symptoms suggestive of SFN, and dyspnea were positive predictors of fatigue. Fit indices of the model were good.
Conclusions:
The model validly explains variation in fatigue. Everyday cognitive failure and depressive symptoms were the most important predictors of fatigue. In addition to physical functioning, cognitive and psychological aspects should be included in the management of sarcoidosis patients
Original languageEnglish
Pages (from-to)S24-S30
JournalRespiratory Medicine
Volume138
DOIs
Publication statusPublished - 2018

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Depression
Medical Records
Outpatients

Keywords

  • ANXIETY
  • ASSESSMENT SCALE
  • Anxiety
  • CLINICAL REMISSION
  • Cognition
  • Depressive symptoms
  • EXERCISE CAPACITY
  • FIT INDEXES
  • Fatigue
  • IDIOPATHIC PULMONARY-FIBROSIS
  • MUSCLE STRENGTH
  • PSYCHOLOGICAL-FACTORS
  • QUALITY-OF-LIFE
  • Quality of life (QoL)
  • SMALL-FIBER NEUROPATHY
  • Sarcoidosis
  • Small fiber neuropathy (SFN)
  • Social support

Cite this

Hendriks, Celine ; Drent, Marjolein ; De Kleijn, Willemien ; Elfferich, Marjon ; Wijnen, Petal ; de Vries, J. / Everyday cognitive failure and depressive symptoms predict fatigue in sarcoidosis : A prospective follow-up study. In: Respiratory Medicine. 2018 ; Vol. 138. pp. S24-S30.
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abstract = "Bachground: Fatigue is a major and disabling problem in sarcoidosis. Knowledge concerning correlates of the development of fatigue and possible interrelationships is lacking.Objective: A conceptual model of fatigue was developed and tested.Methods: Sarcoidosis outpatients (n = 292) of Maastricht University Medical Center completed questionnaires regarding trait anxiety, depressive symptoms, cognitive failure, dyspnea, social support, and small fiber neuropathy (SFN) at baseline. Fatigue was assessed at 6 and 12 months. Sex, age, and time since diagnosis were taken from medical records. Pathways were estimated by means of path analyses in AMOS.Results: Everyday cognitive failure, depressive symptoms, symptoms suggestive of SFN, and dyspnea were positive predictors of fatigue. Fit indices of the model were good.Conclusions: The model validly explains variation in fatigue. Everyday cognitive failure and depressive symptoms were the most important predictors of fatigue. In addition to physical functioning, cognitive and psychological aspects should be included in the management of sarcoidosis patients",
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author = "Celine Hendriks and Marjolein Drent and {De Kleijn}, Willemien and Marjon Elfferich and Petal Wijnen and {de Vries}, J.",
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Everyday cognitive failure and depressive symptoms predict fatigue in sarcoidosis : A prospective follow-up study. / Hendriks, Celine; Drent, Marjolein; De Kleijn, Willemien; Elfferich, Marjon; Wijnen, Petal; de Vries, J.

In: Respiratory Medicine, Vol. 138, 2018, p. S24-S30.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Everyday cognitive failure and depressive symptoms predict fatigue in sarcoidosis

T2 - A prospective follow-up study

AU - Hendriks, Celine

AU - Drent, Marjolein

AU - De Kleijn, Willemien

AU - Elfferich, Marjon

AU - Wijnen, Petal

AU - de Vries, J.

PY - 2018

Y1 - 2018

N2 - Bachground: Fatigue is a major and disabling problem in sarcoidosis. Knowledge concerning correlates of the development of fatigue and possible interrelationships is lacking.Objective: A conceptual model of fatigue was developed and tested.Methods: Sarcoidosis outpatients (n = 292) of Maastricht University Medical Center completed questionnaires regarding trait anxiety, depressive symptoms, cognitive failure, dyspnea, social support, and small fiber neuropathy (SFN) at baseline. Fatigue was assessed at 6 and 12 months. Sex, age, and time since diagnosis were taken from medical records. Pathways were estimated by means of path analyses in AMOS.Results: Everyday cognitive failure, depressive symptoms, symptoms suggestive of SFN, and dyspnea were positive predictors of fatigue. Fit indices of the model were good.Conclusions: The model validly explains variation in fatigue. Everyday cognitive failure and depressive symptoms were the most important predictors of fatigue. In addition to physical functioning, cognitive and psychological aspects should be included in the management of sarcoidosis patients

AB - Bachground: Fatigue is a major and disabling problem in sarcoidosis. Knowledge concerning correlates of the development of fatigue and possible interrelationships is lacking.Objective: A conceptual model of fatigue was developed and tested.Methods: Sarcoidosis outpatients (n = 292) of Maastricht University Medical Center completed questionnaires regarding trait anxiety, depressive symptoms, cognitive failure, dyspnea, social support, and small fiber neuropathy (SFN) at baseline. Fatigue was assessed at 6 and 12 months. Sex, age, and time since diagnosis were taken from medical records. Pathways were estimated by means of path analyses in AMOS.Results: Everyday cognitive failure, depressive symptoms, symptoms suggestive of SFN, and dyspnea were positive predictors of fatigue. Fit indices of the model were good.Conclusions: The model validly explains variation in fatigue. Everyday cognitive failure and depressive symptoms were the most important predictors of fatigue. In addition to physical functioning, cognitive and psychological aspects should be included in the management of sarcoidosis patients

KW - ANXIETY

KW - ASSESSMENT SCALE

KW - Anxiety

KW - CLINICAL REMISSION

KW - Cognition

KW - Depressive symptoms

KW - EXERCISE CAPACITY

KW - FIT INDEXES

KW - Fatigue

KW - IDIOPATHIC PULMONARY-FIBROSIS

KW - MUSCLE STRENGTH

KW - PSYCHOLOGICAL-FACTORS

KW - QUALITY-OF-LIFE

KW - Quality of life (QoL)

KW - SMALL-FIBER NEUROPATHY

KW - Sarcoidosis

KW - Small fiber neuropathy (SFN)

KW - Social support

U2 - 10.1016/j.rmed.2017.11.008

DO - 10.1016/j.rmed.2017.11.008

M3 - Article

VL - 138

SP - S24-S30

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

ER -