Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

Meeke Hoedjes, Sabine Makkes, Jutka Halberstadt, Hanneke Noordam, Carry M Renders, Judith E Bosmans, Olga H van der Baan-Slootweg, Jacob C Seidell

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Abstract

Objective: 

To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL.

Methods: 

In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI.

Results: 

Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains.

Conclusion: 

Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

Original languageEnglish
Pages (from-to)116-128
JournalObesity Facts
Volume11
Issue number2
DOIs
Publication statusPublished - 2018

Fingerprint

Morbid Obesity
quality of life
adolescent
SDS
Weights and Measures
health
Pediatric Obesity
comorbidity
Comorbidity
Inpatients
Linear Models
childhood
questionnaire

Keywords

  • BEHAVIORAL TREATMENT
  • BODY-MASS INDEX
  • CHILDHOOD OBESITY
  • CLINICALLY IMPORTANT DIFFERENCE
  • Health-related quality of life
  • Lifestyle treatment
  • PEDSQL(TM)-4.0
  • PROGRAM
  • RELIABILITY
  • Severe childhood obesity
  • VALIDITY

Cite this

Hoedjes, Meeke ; Makkes, Sabine ; Halberstadt, Jutka ; Noordam, Hanneke ; Renders, Carry M ; Bosmans, Judith E ; van der Baan-Slootweg, Olga H ; Seidell, Jacob C. / Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up. In: Obesity Facts. 2018 ; Vol. 11, No. 2. pp. 116-128.
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keywords = "BEHAVIORAL TREATMENT, BODY-MASS INDEX, CHILDHOOD OBESITY, CLINICALLY IMPORTANT DIFFERENCE, Health-related quality of life, Lifestyle treatment, PEDSQL(TM)-4.0, PROGRAM, RELIABILITY, Severe childhood obesity, VALIDITY",
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year = "2018",
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Hoedjes, M, Makkes, S, Halberstadt, J, Noordam, H, Renders, CM, Bosmans, JE, van der Baan-Slootweg, OH & Seidell, JC 2018, 'Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up' Obesity Facts, vol. 11, no. 2, pp. 116-128. https://doi.org/10.1159/000487328

Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up. / Hoedjes, Meeke; Makkes, Sabine; Halberstadt, Jutka; Noordam, Hanneke; Renders, Carry M; Bosmans, Judith E; van der Baan-Slootweg, Olga H; Seidell, Jacob C.

In: Obesity Facts, Vol. 11, No. 2, 2018, p. 116-128.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

AU - Hoedjes, Meeke

AU - Makkes, Sabine

AU - Halberstadt, Jutka

AU - Noordam, Hanneke

AU - Renders, Carry M

AU - Bosmans, Judith E

AU - van der Baan-Slootweg, Olga H

AU - Seidell, Jacob C

N1 - © 2018 The Author(s) Published by S. Karger GmbH, Freiburg.

PY - 2018

Y1 - 2018

N2 - Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL.Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI.Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains.Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

AB - Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL.Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI.Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains.Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

KW - BEHAVIORAL TREATMENT

KW - BODY-MASS INDEX

KW - CHILDHOOD OBESITY

KW - CLINICALLY IMPORTANT DIFFERENCE

KW - Health-related quality of life

KW - Lifestyle treatment

KW - PEDSQL(TM)-4.0

KW - PROGRAM

KW - RELIABILITY

KW - Severe childhood obesity

KW - VALIDITY

U2 - 10.1159/000487328

DO - 10.1159/000487328

M3 - Article

VL - 11

SP - 116

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JO - Obesity Facts

JF - Obesity Facts

SN - 1662-4025

IS - 2

ER -