The traditional perspective on the political ideology and prejudice relationship holds that political conservatism is associated with prejudice, and that the types of dispositional characteristics associated with conservatism (e.g. low cognitive ability, low Openness) explain this relationship. This conclusion is limited by the limited number and types of groups studied. When researchers use a more heterogeneous array of targets, people across the political spectrum express prejudice against groups with dissimilar values and beliefs. Evidence for this worldview conflict perspective emerges in both politics and religion, as well as individual differences such as Openness, disgust sensitivity and cognitive ability. Although these two perspectives differ substantially, there is some identifiable common ground between them, particularly the assumption of some psychological differences between liberals and conservatives. We discuss some remaining open questions related to worldview conflict reduction, causal processes, the robustness of the assumptions of the traditional perspective, and differences between political elites and the public.