Illness perceptions are associated with mortality among 1552 colorectal cancer survivors

A study from the population-based PROFILES registry

M.S.Y. Thong, A.A. Kaptein, P.A.J. Vissers, G. Vreugdenhil, L.V. van de Poll-Franse

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Abstract

Purpose
Cancer survivors construct perceptions of illness as a (mal)adaptive mechanism. These perceptions motivate/drive subsequent self-management behaviors toward symptoms and treatment that influence health outcomes. Negative illness perceptions have been associated with increased mortality in other chronically ill groups. However, this association is under-researched in cancer survivors. We aimed to explore the association between illness perceptions and mortality in stage I–III progression-free colorectal cancer (CRC) survivors.
Methods
We used data from the population-based Patient Reported Outcomes Following Initial treatment and Long Term Evaluation of Survivorship (PROFILES) registry of two CRC survivorship studies conducted in 2009 and 2010. We accessed clinical data from the Netherlands Cancer Registry, and mortality data from municipal personal records database. Follow-up was until 31 December 2014. Survivors (n = 1552) completed the Brief Illness Perception Questionnaire. Cox proportional hazard models estimated the association between illness perceptions and mortality.
Results
Negative illness perceptions on consequences (adjusted hazard ratio (HRadj) 1.60, 95 % confidence interval (CI) 1.14–2.25) and emotion (HRadj 1.65, 95 % CI 1.18–2.31) were associated with higher mortality, after adjusting for demographic, clinical, and lifestyle factors. Smoking and inadequate physical activity were independently associated with mortality for all Brief Illness Perception Questionnaire (BIPQ) dimensions.
Conclusions
Survivors’ perceptions of their illness are important as these perceptions may influence health outcomes during survivorship period. Clinical practice needs to identify and address maladaptive illness perceptions to support more adaptive self-management behaviors and enhance survivorship.
Implications for cancer survivors
Cancer survivors may benefit from interventions that address potentially maladaptive perceptions and encourage more adaptive self-management behaviors.
Original languageEnglish
Pages (from-to)898–905
JournalJournal of Cancer Survivorship
Volume10
Issue number5
DOIs
Publication statusPublished - 2016

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Survivors
Survival Rate
Confidence Intervals
Neoplasms
Proportional Hazards Models
Netherlands
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Exercise
Surveys and Questionnaires

Cite this

@article{b692cd51b1e44d8ba2b07002e58117f2,
title = "Illness perceptions are associated with mortality among 1552 colorectal cancer survivors: A study from the population-based PROFILES registry",
abstract = "PurposeCancer survivors construct perceptions of illness as a (mal)adaptive mechanism. These perceptions motivate/drive subsequent self-management behaviors toward symptoms and treatment that influence health outcomes. Negative illness perceptions have been associated with increased mortality in other chronically ill groups. However, this association is under-researched in cancer survivors. We aimed to explore the association between illness perceptions and mortality in stage I–III progression-free colorectal cancer (CRC) survivors.MethodsWe used data from the population-based Patient Reported Outcomes Following Initial treatment and Long Term Evaluation of Survivorship (PROFILES) registry of two CRC survivorship studies conducted in 2009 and 2010. We accessed clinical data from the Netherlands Cancer Registry, and mortality data from municipal personal records database. Follow-up was until 31 December 2014. Survivors (n = 1552) completed the Brief Illness Perception Questionnaire. Cox proportional hazard models estimated the association between illness perceptions and mortality.ResultsNegative illness perceptions on consequences (adjusted hazard ratio (HRadj) 1.60, 95 {\%} confidence interval (CI) 1.14–2.25) and emotion (HRadj 1.65, 95 {\%} CI 1.18–2.31) were associated with higher mortality, after adjusting for demographic, clinical, and lifestyle factors. Smoking and inadequate physical activity were independently associated with mortality for all Brief Illness Perception Questionnaire (BIPQ) dimensions.ConclusionsSurvivors’ perceptions of their illness are important as these perceptions may influence health outcomes during survivorship period. Clinical practice needs to identify and address maladaptive illness perceptions to support more adaptive self-management behaviors and enhance survivorship.Implications for cancer survivorsCancer survivors may benefit from interventions that address potentially maladaptive perceptions and encourage more adaptive self-management behaviors.",
author = "M.S.Y. Thong and A.A. Kaptein and P.A.J. Vissers and G. Vreugdenhil and {van de Poll-Franse}, L.V.",
year = "2016",
doi = "10.1007/s11764-016-0536-5",
language = "English",
volume = "10",
pages = "898–905",
journal = "Journal of Cancer Survivorship",
issn = "1932-2259",
publisher = "Springer New York",
number = "5",

}

Illness perceptions are associated with mortality among 1552 colorectal cancer survivors : A study from the population-based PROFILES registry. / Thong, M.S.Y.; Kaptein, A.A.; Vissers, P.A.J.; Vreugdenhil, G.; van de Poll-Franse, L.V.

In: Journal of Cancer Survivorship, Vol. 10, No. 5, 2016, p. 898–905.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Illness perceptions are associated with mortality among 1552 colorectal cancer survivors

T2 - A study from the population-based PROFILES registry

AU - Thong, M.S.Y.

AU - Kaptein, A.A.

AU - Vissers, P.A.J.

AU - Vreugdenhil, G.

AU - van de Poll-Franse, L.V.

PY - 2016

Y1 - 2016

N2 - PurposeCancer survivors construct perceptions of illness as a (mal)adaptive mechanism. These perceptions motivate/drive subsequent self-management behaviors toward symptoms and treatment that influence health outcomes. Negative illness perceptions have been associated with increased mortality in other chronically ill groups. However, this association is under-researched in cancer survivors. We aimed to explore the association between illness perceptions and mortality in stage I–III progression-free colorectal cancer (CRC) survivors.MethodsWe used data from the population-based Patient Reported Outcomes Following Initial treatment and Long Term Evaluation of Survivorship (PROFILES) registry of two CRC survivorship studies conducted in 2009 and 2010. We accessed clinical data from the Netherlands Cancer Registry, and mortality data from municipal personal records database. Follow-up was until 31 December 2014. Survivors (n = 1552) completed the Brief Illness Perception Questionnaire. Cox proportional hazard models estimated the association between illness perceptions and mortality.ResultsNegative illness perceptions on consequences (adjusted hazard ratio (HRadj) 1.60, 95 % confidence interval (CI) 1.14–2.25) and emotion (HRadj 1.65, 95 % CI 1.18–2.31) were associated with higher mortality, after adjusting for demographic, clinical, and lifestyle factors. Smoking and inadequate physical activity were independently associated with mortality for all Brief Illness Perception Questionnaire (BIPQ) dimensions.ConclusionsSurvivors’ perceptions of their illness are important as these perceptions may influence health outcomes during survivorship period. Clinical practice needs to identify and address maladaptive illness perceptions to support more adaptive self-management behaviors and enhance survivorship.Implications for cancer survivorsCancer survivors may benefit from interventions that address potentially maladaptive perceptions and encourage more adaptive self-management behaviors.

AB - PurposeCancer survivors construct perceptions of illness as a (mal)adaptive mechanism. These perceptions motivate/drive subsequent self-management behaviors toward symptoms and treatment that influence health outcomes. Negative illness perceptions have been associated with increased mortality in other chronically ill groups. However, this association is under-researched in cancer survivors. We aimed to explore the association between illness perceptions and mortality in stage I–III progression-free colorectal cancer (CRC) survivors.MethodsWe used data from the population-based Patient Reported Outcomes Following Initial treatment and Long Term Evaluation of Survivorship (PROFILES) registry of two CRC survivorship studies conducted in 2009 and 2010. We accessed clinical data from the Netherlands Cancer Registry, and mortality data from municipal personal records database. Follow-up was until 31 December 2014. Survivors (n = 1552) completed the Brief Illness Perception Questionnaire. Cox proportional hazard models estimated the association between illness perceptions and mortality.ResultsNegative illness perceptions on consequences (adjusted hazard ratio (HRadj) 1.60, 95 % confidence interval (CI) 1.14–2.25) and emotion (HRadj 1.65, 95 % CI 1.18–2.31) were associated with higher mortality, after adjusting for demographic, clinical, and lifestyle factors. Smoking and inadequate physical activity were independently associated with mortality for all Brief Illness Perception Questionnaire (BIPQ) dimensions.ConclusionsSurvivors’ perceptions of their illness are important as these perceptions may influence health outcomes during survivorship period. Clinical practice needs to identify and address maladaptive illness perceptions to support more adaptive self-management behaviors and enhance survivorship.Implications for cancer survivorsCancer survivors may benefit from interventions that address potentially maladaptive perceptions and encourage more adaptive self-management behaviors.

U2 - 10.1007/s11764-016-0536-5

DO - 10.1007/s11764-016-0536-5

M3 - Article

VL - 10

SP - 898

EP - 905

JO - Journal of Cancer Survivorship

JF - Journal of Cancer Survivorship

SN - 1932-2259

IS - 5

ER -