Long term fMRI adaptation depends on adapter response in face-selective cortex

Daphne Stam, Yun-An Huang, Kristof Vansteelandt, Stefan Sunaert, Ron Peeters, Charlotte Sleurs, Leia Vrancken, Louise Emsell, Rufin Vogels, Mathieu Vandenbulcke, Jan Van den Stock

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Repetition suppression (RS) reflects a neural attenuation during repeated stimulation. We used fMRI and the subsequent memory paradigm to test the predictive coding hypothesis for RS during visual memory processing by investigating the interaction between RS and differences due to memory in category-selective cortex (FFA, pSTS, PPA, and RSC). Fifty-six participants encoded face and house stimuli twice, followed by an immediate and delayed (48 h) recognition memory assessment. Linear Mixed Model analyses with repetition, subsequent recognition performance, and their interaction as fixed effects revealed that absolute RS during encoding interacts with probability of future remembrance in face-selective cortex. This effect was not observed for relative RS, i.e. when controlled for adapter-response. The findings also reveal an association between adapter response and RS, both for short and long term (48h) intervals, after controlling for the mathematical dependence between both measures. These combined findings are challenging for predictive coding models of visual memory and are more compatible with adapter-related and familiarity accounts.

Original languageEnglish
Pages (from-to)712
JournalCommunications biology
Volume4
Issue number1
DOIs
Publication statusPublished - 2021
Externally publishedYes

Keywords

  • Adult
  • Cerebral Cortex/physiology
  • Eye Movements
  • Face/anatomy & histology
  • Female
  • Humans
  • Linear Models
  • Magnetic Resonance Imaging
  • Male
  • Memory, Long-Term
  • Middle Aged
  • Perception
  • Visual Perception
  • Young Adult

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