Pain as a risk factor for common mental disorders. Results from the Netherlands Mental Health Survey and Incidence Study-2

A longitudinal, population-based study

E.W. de Heer, M.T. Have, H.W.J. van Marwijk, J. Dekker, R. Graaf, A.T.F. Beekman, C.M. van der Feltz-Cornelis

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Pain might be an important risk factor for common mental disorders. Insight into the longitudinal association between pain and common mental disorders in the general adult population could help improve prevention and treatment strategies. Data were used from the first 2 waves of the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the Dutch general population aged 18 to 64 years at baseline (N = 5303). Persons without a mental disorder 12 months before baseline were selected as the at-risk group (n=4974 for any mood disorder; n=4979 for any anxiety disorder; and n=5073 for any substance use disorder). Pain severity and interference due to pain in the past month were measured at baseline using the Short Form Health Survey. DSM-IV mental disorders were assessed at both waves using the Composite International Diagnostic Interview version 3.0. Moderate to very severe pain was associated with a higher risk of mood (odds ratio [OR] = 2.10, 95% confidence interval [CI] = 1.33-3.29) or anxiety disorders (OR = 2.12, 95% CI = 1.27-3.55). Moderate to very severe interference due to pain was also associated with a higher risk of mood (OR=2.14, 95% CI=1.30-3.54) or anxiety disorders (OR=1.92, 95% CI =1.05-3.52). Pain was not significantly associated with substance use disorders. No interaction effects were found between pain severity or interference due to pain and a previous history of mental disorders. Moderate to severe pain and interference due to pain are strong risk factors for first-incident or recurrent mood and anxiety disorders, independent of other mental disorders. Pain management programs could therefore possibly also serve as a preventative program for mental disorders.

Original languageEnglish
Pages (from-to)712-718
JournalPain
Volume159
Issue number4
DOIs
Publication statusPublished - 2018

Fingerprint

Health Surveys
Netherlands
Mental Health
Odds Ratio
Confidence Intervals
Pain Management
Diagnostic and Statistical Manual of Mental Disorders
Interviews

Keywords

  • ANXIETY
  • Anxiety disorders
  • BACK-PAIN
  • BRAIN
  • COMORBIDITY
  • Common mental disorders
  • DEPRESSION
  • EUROPE
  • General population
  • IMPACT
  • Interference due to pain
  • Mood disorders
  • PREVALENCE
  • Pain
  • Pain severity
  • SYMPTOMS
  • Substance use disorders
  • VERSION

Cite this

@article{d708dc4b8f0e48dbbb360fa180e4cd3b,
title = "Pain as a risk factor for common mental disorders. Results from the Netherlands Mental Health Survey and Incidence Study-2: A longitudinal, population-based study",
abstract = "Pain might be an important risk factor for common mental disorders. Insight into the longitudinal association between pain and common mental disorders in the general adult population could help improve prevention and treatment strategies. Data were used from the first 2 waves of the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the Dutch general population aged 18 to 64 years at baseline (N = 5303). Persons without a mental disorder 12 months before baseline were selected as the at-risk group (n=4974 for any mood disorder; n=4979 for any anxiety disorder; and n=5073 for any substance use disorder). Pain severity and interference due to pain in the past month were measured at baseline using the Short Form Health Survey. DSM-IV mental disorders were assessed at both waves using the Composite International Diagnostic Interview version 3.0. Moderate to very severe pain was associated with a higher risk of mood (odds ratio [OR] = 2.10, 95{\%} confidence interval [CI] = 1.33-3.29) or anxiety disorders (OR = 2.12, 95{\%} CI = 1.27-3.55). Moderate to very severe interference due to pain was also associated with a higher risk of mood (OR=2.14, 95{\%} CI=1.30-3.54) or anxiety disorders (OR=1.92, 95{\%} CI =1.05-3.52). Pain was not significantly associated with substance use disorders. No interaction effects were found between pain severity or interference due to pain and a previous history of mental disorders. Moderate to severe pain and interference due to pain are strong risk factors for first-incident or recurrent mood and anxiety disorders, independent of other mental disorders. Pain management programs could therefore possibly also serve as a preventative program for mental disorders.",
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author = "{de Heer}, E.W. and M.T. Have and {van Marwijk}, H.W.J. and J. Dekker and R. Graaf and A.T.F. Beekman and {van der Feltz-Cornelis}, C.M.",
year = "2018",
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language = "English",
volume = "159",
pages = "712--718",
journal = "Pain",
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Pain as a risk factor for common mental disorders. Results from the Netherlands Mental Health Survey and Incidence Study-2 : A longitudinal, population-based study. / de Heer, E.W.; Have, M.T.; van Marwijk, H.W.J.; Dekker, J.; Graaf, R.; Beekman, A.T.F.; van der Feltz-Cornelis, C.M.

In: Pain, Vol. 159, No. 4, 2018, p. 712-718.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Pain as a risk factor for common mental disorders. Results from the Netherlands Mental Health Survey and Incidence Study-2

T2 - A longitudinal, population-based study

AU - de Heer, E.W.

AU - Have, M.T.

AU - van Marwijk, H.W.J.

AU - Dekker, J.

AU - Graaf, R.

AU - Beekman, A.T.F.

AU - van der Feltz-Cornelis, C.M.

PY - 2018

Y1 - 2018

N2 - Pain might be an important risk factor for common mental disorders. Insight into the longitudinal association between pain and common mental disorders in the general adult population could help improve prevention and treatment strategies. Data were used from the first 2 waves of the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the Dutch general population aged 18 to 64 years at baseline (N = 5303). Persons without a mental disorder 12 months before baseline were selected as the at-risk group (n=4974 for any mood disorder; n=4979 for any anxiety disorder; and n=5073 for any substance use disorder). Pain severity and interference due to pain in the past month were measured at baseline using the Short Form Health Survey. DSM-IV mental disorders were assessed at both waves using the Composite International Diagnostic Interview version 3.0. Moderate to very severe pain was associated with a higher risk of mood (odds ratio [OR] = 2.10, 95% confidence interval [CI] = 1.33-3.29) or anxiety disorders (OR = 2.12, 95% CI = 1.27-3.55). Moderate to very severe interference due to pain was also associated with a higher risk of mood (OR=2.14, 95% CI=1.30-3.54) or anxiety disorders (OR=1.92, 95% CI =1.05-3.52). Pain was not significantly associated with substance use disorders. No interaction effects were found between pain severity or interference due to pain and a previous history of mental disorders. Moderate to severe pain and interference due to pain are strong risk factors for first-incident or recurrent mood and anxiety disorders, independent of other mental disorders. Pain management programs could therefore possibly also serve as a preventative program for mental disorders.

AB - Pain might be an important risk factor for common mental disorders. Insight into the longitudinal association between pain and common mental disorders in the general adult population could help improve prevention and treatment strategies. Data were used from the first 2 waves of the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the Dutch general population aged 18 to 64 years at baseline (N = 5303). Persons without a mental disorder 12 months before baseline were selected as the at-risk group (n=4974 for any mood disorder; n=4979 for any anxiety disorder; and n=5073 for any substance use disorder). Pain severity and interference due to pain in the past month were measured at baseline using the Short Form Health Survey. DSM-IV mental disorders were assessed at both waves using the Composite International Diagnostic Interview version 3.0. Moderate to very severe pain was associated with a higher risk of mood (odds ratio [OR] = 2.10, 95% confidence interval [CI] = 1.33-3.29) or anxiety disorders (OR = 2.12, 95% CI = 1.27-3.55). Moderate to very severe interference due to pain was also associated with a higher risk of mood (OR=2.14, 95% CI=1.30-3.54) or anxiety disorders (OR=1.92, 95% CI =1.05-3.52). Pain was not significantly associated with substance use disorders. No interaction effects were found between pain severity or interference due to pain and a previous history of mental disorders. Moderate to severe pain and interference due to pain are strong risk factors for first-incident or recurrent mood and anxiety disorders, independent of other mental disorders. Pain management programs could therefore possibly also serve as a preventative program for mental disorders.

KW - ANXIETY

KW - Anxiety disorders

KW - BACK-PAIN

KW - BRAIN

KW - COMORBIDITY

KW - Common mental disorders

KW - DEPRESSION

KW - EUROPE

KW - General population

KW - IMPACT

KW - Interference due to pain

KW - Mood disorders

KW - PREVALENCE

KW - Pain

KW - Pain severity

KW - SYMPTOMS

KW - Substance use disorders

KW - VERSION

U2 - 10.1097/j.pain.0000000000001133

DO - 10.1097/j.pain.0000000000001133

M3 - Article

VL - 159

SP - 712

EP - 718

JO - Pain

JF - Pain

SN - 0304-3959

IS - 4

ER -