Patient-centered development of <i>Embrace Pain</i> an online acceptance and commitment therapy intervention for cancer survivors with chronic painful chemotherapy-induced peripheral neuropathy

Danielle L. van de Graaf, Tom Smeets, Marije L. van der Lee, Hester R. Trompetter, Aafke Baars-Seebregts, Elin Borosund, Lise Solberg Nes, Karlein M. G. Schreurs, Floortje Mols

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background: Around 30% of cancer survivors suffer from chemotherapy-induced peripheral neuropathy (CIPN) = 6 months after completion of chemotherapy, which comes with limitations in daily functioning and worsened quality of life(QoL). Treatment options are scarce. Our aim was to develop an online self-help intervention based on Acceptance and Commitment Therapy (ACT) to reduce pain interference in cancer survivors experiencing painful chronic CIPN.Material and methods: This article applied a patient-centered design process using the Center for eHealth Research (CeHRes) roadmap. User needs were examined using online semi-structured inter-views with patients and experts (N=23). Interviews were transcribed verbatim and analyzed using thematic analysis. Personas were created based on interviews. Intervention content was based on identified user needs and ACT. Content and design were finalized using low-fidelity prototype testing (N=5), and high-fidelity prototype testing (N=7).Results: Patients appreciated and agreed with the elements of ACT, had varying guidance needs, and wanted to have autonomy (e.g., moment and duration of use). Additionally, it was important to be aware that patients have had a life-threatening disease which directly relates to the symptoms they experience. Patients reported to prefer a user-friendly and accessible intervention. Similar points also emerged in the expert interviews. The final intervention, named Embrace Pain, includes six sessions. Session content is based on psychoeducation and all ACT processes. Further interpretation of the intervention (such as quotes, guidance, and multimedia choices) is based on the interviews.Conclusion: This development demonstrated how a patient-centered design process from a theoretical framework can be applied. Theory-driven content was used as the basis of the intervention. Findings show an online ACT intervention designed for cancer survivors with painful chronic CIPN.
Original languageEnglish
Number of pages13
JournalActa Oncologica
Early online dateMar 2023
DOIs
Publication statusPublished - 19 Mar 2023

Keywords

  • PROFILES registry
  • Acceptance and commitment therapy
  • Cancer survivors
  • Chemotherapy-induced peripheral neuropathy
  • eHealth
  • Online

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