Postpartum depression after mild and severe preeclampsia

Meeke Hoedjes, Durk Berks, Ineke Vogel, Arie Franx, Meike Bangma, Anne-Sophie E Darlington, Willy Visser, Johannes J Duvekot, J Dik F Habbema, Eric A P Steegers, Hein Raat

Research output: Contribution to journalArticleScientificpeer-review

Abstract

OBJECTIVE: To describe the prevalence of postpartum depressive symptoms after preeclampsia, to assess the extent to which the prevalence of postpartum depressive symptoms differs after mild and severe preeclampsia, and to investigate which factors contribute to such differences.

METHODS: Women diagnosed with preeclampsia (n=161) completed the Edinburgh Postnatal Depression Scale (EPDS) at 6, 12, or 26 weeks postpartum. Multiple logistic regression analysis was used to investigate the association between severity of preeclampsia, contributing factors and postpartum depression (PPD) (1) at any time during the first 26 weeks postpartum and (2) accounting for longitudinal observations at three time points.

RESULTS: After mild preeclampsia, 23% reported postpartum depressive symptoms at any time up to 26 weeks postpartum compared to 44% after severe preeclampsia (unadjusted odds ratio [OR] 2.65, 95% confidence interval [CI] 1.16-6.05) for depression at any time up to 26 weeks postpartum (unadjusted OR 2.57, 95% CI, 1.14-5.76) while accounting for longitudinal observations. Admission to the neonatal intensive care unit (NICU) (adjusted OR 3.19, 95% CI 1.15-8.89) and perinatal death (adjusted OR 2.96, 95% CI 1.09-8.03) contributed to this difference.

CONCLUSIONS: It appears that not the severity of preeclampsia itself but rather the consequences of the severity of the disease (especially admission to the NICU and perinatal death) cause postpartum depressive symptoms. Obstetricians should be aware of the high risk of postpartum depressive symptoms after severe preeclampsia, particularly among women whose infant has been admitted to the NICU or has died.

Original languageEnglish
Pages (from-to)1535-42
Number of pages8
JournalJournal of women's health (2002)
Volume20
Issue number10
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Postpartum Depression
Depression
Neonatal Intensive Care Units
Odds Ratio
Confidence Intervals
Logistic Models

Keywords

  • Adolescent
  • Adult
  • Depression, Postpartum/epidemiology
  • Female
  • Humans
  • Netherlands/epidemiology
  • Pre-Eclampsia/physiopathology
  • Pregnancy
  • Pregnancy Complications
  • Young Adult

Cite this

Hoedjes, M., Berks, D., Vogel, I., Franx, A., Bangma, M., Darlington, A-S. E., ... Raat, H. (2011). Postpartum depression after mild and severe preeclampsia. Journal of women's health (2002), 20(10), 1535-42. https://doi.org/10.1089/jwh.2010.2584
Hoedjes, Meeke ; Berks, Durk ; Vogel, Ineke ; Franx, Arie ; Bangma, Meike ; Darlington, Anne-Sophie E ; Visser, Willy ; Duvekot, Johannes J ; Habbema, J Dik F ; Steegers, Eric A P ; Raat, Hein. / Postpartum depression after mild and severe preeclampsia. In: Journal of women's health (2002). 2011 ; Vol. 20, No. 10. pp. 1535-42.
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abstract = "OBJECTIVE: To describe the prevalence of postpartum depressive symptoms after preeclampsia, to assess the extent to which the prevalence of postpartum depressive symptoms differs after mild and severe preeclampsia, and to investigate which factors contribute to such differences.METHODS: Women diagnosed with preeclampsia (n=161) completed the Edinburgh Postnatal Depression Scale (EPDS) at 6, 12, or 26 weeks postpartum. Multiple logistic regression analysis was used to investigate the association between severity of preeclampsia, contributing factors and postpartum depression (PPD) (1) at any time during the first 26 weeks postpartum and (2) accounting for longitudinal observations at three time points.RESULTS: After mild preeclampsia, 23{\%} reported postpartum depressive symptoms at any time up to 26 weeks postpartum compared to 44{\%} after severe preeclampsia (unadjusted odds ratio [OR] 2.65, 95{\%} confidence interval [CI] 1.16-6.05) for depression at any time up to 26 weeks postpartum (unadjusted OR 2.57, 95{\%} CI, 1.14-5.76) while accounting for longitudinal observations. Admission to the neonatal intensive care unit (NICU) (adjusted OR 3.19, 95{\%} CI 1.15-8.89) and perinatal death (adjusted OR 2.96, 95{\%} CI 1.09-8.03) contributed to this difference.CONCLUSIONS: It appears that not the severity of preeclampsia itself but rather the consequences of the severity of the disease (especially admission to the NICU and perinatal death) cause postpartum depressive symptoms. Obstetricians should be aware of the high risk of postpartum depressive symptoms after severe preeclampsia, particularly among women whose infant has been admitted to the NICU or has died.",
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Hoedjes, M, Berks, D, Vogel, I, Franx, A, Bangma, M, Darlington, A-SE, Visser, W, Duvekot, JJ, Habbema, JDF, Steegers, EAP & Raat, H 2011, 'Postpartum depression after mild and severe preeclampsia', Journal of women's health (2002), vol. 20, no. 10, pp. 1535-42. https://doi.org/10.1089/jwh.2010.2584

Postpartum depression after mild and severe preeclampsia. / Hoedjes, Meeke; Berks, Durk; Vogel, Ineke; Franx, Arie; Bangma, Meike; Darlington, Anne-Sophie E; Visser, Willy; Duvekot, Johannes J; Habbema, J Dik F; Steegers, Eric A P; Raat, Hein.

In: Journal of women's health (2002), Vol. 20, No. 10, 2011, p. 1535-42.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Postpartum depression after mild and severe preeclampsia

AU - Hoedjes, Meeke

AU - Berks, Durk

AU - Vogel, Ineke

AU - Franx, Arie

AU - Bangma, Meike

AU - Darlington, Anne-Sophie E

AU - Visser, Willy

AU - Duvekot, Johannes J

AU - Habbema, J Dik F

AU - Steegers, Eric A P

AU - Raat, Hein

PY - 2011

Y1 - 2011

N2 - OBJECTIVE: To describe the prevalence of postpartum depressive symptoms after preeclampsia, to assess the extent to which the prevalence of postpartum depressive symptoms differs after mild and severe preeclampsia, and to investigate which factors contribute to such differences.METHODS: Women diagnosed with preeclampsia (n=161) completed the Edinburgh Postnatal Depression Scale (EPDS) at 6, 12, or 26 weeks postpartum. Multiple logistic regression analysis was used to investigate the association between severity of preeclampsia, contributing factors and postpartum depression (PPD) (1) at any time during the first 26 weeks postpartum and (2) accounting for longitudinal observations at three time points.RESULTS: After mild preeclampsia, 23% reported postpartum depressive symptoms at any time up to 26 weeks postpartum compared to 44% after severe preeclampsia (unadjusted odds ratio [OR] 2.65, 95% confidence interval [CI] 1.16-6.05) for depression at any time up to 26 weeks postpartum (unadjusted OR 2.57, 95% CI, 1.14-5.76) while accounting for longitudinal observations. Admission to the neonatal intensive care unit (NICU) (adjusted OR 3.19, 95% CI 1.15-8.89) and perinatal death (adjusted OR 2.96, 95% CI 1.09-8.03) contributed to this difference.CONCLUSIONS: It appears that not the severity of preeclampsia itself but rather the consequences of the severity of the disease (especially admission to the NICU and perinatal death) cause postpartum depressive symptoms. Obstetricians should be aware of the high risk of postpartum depressive symptoms after severe preeclampsia, particularly among women whose infant has been admitted to the NICU or has died.

AB - OBJECTIVE: To describe the prevalence of postpartum depressive symptoms after preeclampsia, to assess the extent to which the prevalence of postpartum depressive symptoms differs after mild and severe preeclampsia, and to investigate which factors contribute to such differences.METHODS: Women diagnosed with preeclampsia (n=161) completed the Edinburgh Postnatal Depression Scale (EPDS) at 6, 12, or 26 weeks postpartum. Multiple logistic regression analysis was used to investigate the association between severity of preeclampsia, contributing factors and postpartum depression (PPD) (1) at any time during the first 26 weeks postpartum and (2) accounting for longitudinal observations at three time points.RESULTS: After mild preeclampsia, 23% reported postpartum depressive symptoms at any time up to 26 weeks postpartum compared to 44% after severe preeclampsia (unadjusted odds ratio [OR] 2.65, 95% confidence interval [CI] 1.16-6.05) for depression at any time up to 26 weeks postpartum (unadjusted OR 2.57, 95% CI, 1.14-5.76) while accounting for longitudinal observations. Admission to the neonatal intensive care unit (NICU) (adjusted OR 3.19, 95% CI 1.15-8.89) and perinatal death (adjusted OR 2.96, 95% CI 1.09-8.03) contributed to this difference.CONCLUSIONS: It appears that not the severity of preeclampsia itself but rather the consequences of the severity of the disease (especially admission to the NICU and perinatal death) cause postpartum depressive symptoms. Obstetricians should be aware of the high risk of postpartum depressive symptoms after severe preeclampsia, particularly among women whose infant has been admitted to the NICU or has died.

KW - Adolescent

KW - Adult

KW - Depression, Postpartum/epidemiology

KW - Female

KW - Humans

KW - Netherlands/epidemiology

KW - Pre-Eclampsia/physiopathology

KW - Pregnancy

KW - Pregnancy Complications

KW - Young Adult

U2 - 10.1089/jwh.2010.2584

DO - 10.1089/jwh.2010.2584

M3 - Article

VL - 20

SP - 1535

EP - 1542

JO - Journal of women's health (2002)

JF - Journal of women's health (2002)

SN - 1540-9996

IS - 10

ER -