Pre-diagnosis quality of life (QoL) in patients with hematuria: Comparison of bladder cancer with other causes

C.A. Goossens-Laan, P.J.M. Kil, J.L. Bosch, J. de Vries

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Abstract

Purpose
To examine quality of life (QoL), health status, sexual function, and anxiety in patients with primary hematuria who later appear to have bladder cancer (BC) and patients with other diagnoses.
Methods
From July 2007 to July 2010, 598 patients with primary hematuria were enrolled in this prospective, multicenter study. Questionnaires (WHOQOL-BREF, SF-12, IIEF, STAI-10-item Trait) were completed before cystoscopy. Diagnosis was subsequently derived from medical files. BC patients were compared with patients with other causes of hematuria.
Results
Cancer was diagnosed in 131 patients (21.9 %), including 102 patients (17.1 %) with BC. No differences were found in the WHOQOL-BREF versus SF-12 psychological or physical health domains. The erectile function was significantly worse in the BC group (9.3 vs. 14.6 for OC, p = 0.02). Patients with muscle-invasive BC (MIBC) had the lowest percentage anxious personalities of all BC patients (p = 0.04).
Conclusions
Cancer was found in 21.9 % of the patients with hematuria. Pre-diagnosis patients with BC have comparable QoL and HS to patients with OC. Erectile dysfunction was highest in patients with BC. MIBC patients had the lowest percentage anxious personalities of the patients with BC.
Keywords: Quality of life, Health status, Hematuria, Bladder cancer, Erectile dysfunction
Original languageEnglish
Pages (from-to)309-315
JournalQuality of Life Research
Volume22
Issue number2
DOIs
Publication statusPublished - 2013

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Hematuria
Muscles
Cystoscopy
Multicenter Studies

Cite this

@article{300b9d930dc84f71b340d665afffa7b2,
title = "Pre-diagnosis quality of life (QoL) in patients with hematuria: Comparison of bladder cancer with other causes",
abstract = "PurposeTo examine quality of life (QoL), health status, sexual function, and anxiety in patients with primary hematuria who later appear to have bladder cancer (BC) and patients with other diagnoses.MethodsFrom July 2007 to July 2010, 598 patients with primary hematuria were enrolled in this prospective, multicenter study. Questionnaires (WHOQOL-BREF, SF-12, IIEF, STAI-10-item Trait) were completed before cystoscopy. Diagnosis was subsequently derived from medical files. BC patients were compared with patients with other causes of hematuria.ResultsCancer was diagnosed in 131 patients (21.9 {\%}), including 102 patients (17.1 {\%}) with BC. No differences were found in the WHOQOL-BREF versus SF-12 psychological or physical health domains. The erectile function was significantly worse in the BC group (9.3 vs. 14.6 for OC, p = 0.02). Patients with muscle-invasive BC (MIBC) had the lowest percentage anxious personalities of all BC patients (p = 0.04).ConclusionsCancer was found in 21.9 {\%} of the patients with hematuria. Pre-diagnosis patients with BC have comparable QoL and HS to patients with OC. Erectile dysfunction was highest in patients with BC. MIBC patients had the lowest percentage anxious personalities of the patients with BC.Keywords: Quality of life, Health status, Hematuria, Bladder cancer, Erectile dysfunction",
author = "C.A. Goossens-Laan and P.J.M. Kil and J.L. Bosch and {de Vries}, J.",
year = "2013",
doi = "10.1007/s11136-012-0163-1",
language = "English",
volume = "22",
pages = "309--315",
journal = "Quality of Life Research",
issn = "0962-9343",
publisher = "Springer",
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}

Pre-diagnosis quality of life (QoL) in patients with hematuria : Comparison of bladder cancer with other causes. / Goossens-Laan, C.A.; Kil, P.J.M.; Bosch, J.L.; de Vries, J.

In: Quality of Life Research, Vol. 22, No. 2, 2013, p. 309-315.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Pre-diagnosis quality of life (QoL) in patients with hematuria

T2 - Comparison of bladder cancer with other causes

AU - Goossens-Laan, C.A.

AU - Kil, P.J.M.

AU - Bosch, J.L.

AU - de Vries, J.

PY - 2013

Y1 - 2013

N2 - PurposeTo examine quality of life (QoL), health status, sexual function, and anxiety in patients with primary hematuria who later appear to have bladder cancer (BC) and patients with other diagnoses.MethodsFrom July 2007 to July 2010, 598 patients with primary hematuria were enrolled in this prospective, multicenter study. Questionnaires (WHOQOL-BREF, SF-12, IIEF, STAI-10-item Trait) were completed before cystoscopy. Diagnosis was subsequently derived from medical files. BC patients were compared with patients with other causes of hematuria.ResultsCancer was diagnosed in 131 patients (21.9 %), including 102 patients (17.1 %) with BC. No differences were found in the WHOQOL-BREF versus SF-12 psychological or physical health domains. The erectile function was significantly worse in the BC group (9.3 vs. 14.6 for OC, p = 0.02). Patients with muscle-invasive BC (MIBC) had the lowest percentage anxious personalities of all BC patients (p = 0.04).ConclusionsCancer was found in 21.9 % of the patients with hematuria. Pre-diagnosis patients with BC have comparable QoL and HS to patients with OC. Erectile dysfunction was highest in patients with BC. MIBC patients had the lowest percentage anxious personalities of the patients with BC.Keywords: Quality of life, Health status, Hematuria, Bladder cancer, Erectile dysfunction

AB - PurposeTo examine quality of life (QoL), health status, sexual function, and anxiety in patients with primary hematuria who later appear to have bladder cancer (BC) and patients with other diagnoses.MethodsFrom July 2007 to July 2010, 598 patients with primary hematuria were enrolled in this prospective, multicenter study. Questionnaires (WHOQOL-BREF, SF-12, IIEF, STAI-10-item Trait) were completed before cystoscopy. Diagnosis was subsequently derived from medical files. BC patients were compared with patients with other causes of hematuria.ResultsCancer was diagnosed in 131 patients (21.9 %), including 102 patients (17.1 %) with BC. No differences were found in the WHOQOL-BREF versus SF-12 psychological or physical health domains. The erectile function was significantly worse in the BC group (9.3 vs. 14.6 for OC, p = 0.02). Patients with muscle-invasive BC (MIBC) had the lowest percentage anxious personalities of all BC patients (p = 0.04).ConclusionsCancer was found in 21.9 % of the patients with hematuria. Pre-diagnosis patients with BC have comparable QoL and HS to patients with OC. Erectile dysfunction was highest in patients with BC. MIBC patients had the lowest percentage anxious personalities of the patients with BC.Keywords: Quality of life, Health status, Hematuria, Bladder cancer, Erectile dysfunction

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SP - 309

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JO - Quality of Life Research

JF - Quality of Life Research

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