Prevalence and correlates of mental health problems in prostate cancer survivors: A case control study comparing survivors with general population peers

M. van Stam, H.G. van der Poel, J.L.H.R. Bosch, C.N. Tiller, S. Horenblas, F. Mols, N.K. Aaronson

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Objective
The purpose of this study was to identify factors associated with mental health (MH) problems in prostate cancer (PC) survivors. Toward this end, we evaluated (1) differences in the prevalence of MH problems between PC survivors and age-matched men from the general population (GenPop) and (2) correlates of MH in PC survivors and the GenPop.
Methods and materials
In this observational case-control study, we age-matched PC survivors (n = 644, alive≥5 y after diagnosis of a stage I–IV carcinoma) recruited from Dutch community hospitals (Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship registry) with GenPop peers (n = 644) selected from a population-based sample recruited in general practices (NIVEL). MH was operationalized using the 5-item Mental Health Inventory of the Short Form Health Survey (SF-36). Potential correlates of MH included sociodemographic characteristics, health-related quality of life scores, and clinical characteristics (PC survivors only). We used analysis of (co)variance and chi-square tests to address the 2 research questions.
Results
We observed clinically relevant MH symptoms in 14% of the PC survivors and 6% of the GenPop controls (P<0.01, odds ratio = 2.45 [1.66–3.62]). The most important correlates of lower MH scores in the PC survivors were being widowed, a lower educational level, lower general health perceptions, more bodily pain and urinary bother, and less sexual satisfaction. The most important correlates of lower MH scores in the GenPop were as follows: lower general health perceptions, more role limitations because of physical problems, and more bodily pain.
Conclusions
Our results indicate that long-term PC survivors have poorer MH, as assessed by the 5-item Mental Health Inventory questionnaire, than men of a comparable age from the GenPop without a history of PC. Attention to potentially modifiable factors associated with MH problems in PC survivors, such as urinary function and its related bother, bodily pain, and sexual satisfaction, may help to prevent or limit MH problems in this survivor population.
Original languageEnglish
Pages (from-to)531.e1-531.e7
JournalUrologic Oncology: Seminars and Original Investigations
Volume35
Issue number8
DOIs
Publication statusPublished - 2017

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Survivors
Mental Health
Orgasm
Widowhood
Equipment and Supplies
Community Hospital
Chi-Square Distribution
Health Surveys
General Practice
Survival Rate
Odds Ratio

Cite this

van Stam, M. ; van der Poel, H.G. ; Bosch, J.L.H.R. ; Tiller, C.N. ; Horenblas, S. ; Mols, F. ; Aaronson, N.K. / Prevalence and correlates of mental health problems in prostate cancer survivors : A case control study comparing survivors with general population peers. In: Urologic Oncology: Seminars and Original Investigations. 2017 ; Vol. 35, No. 8. pp. 531.e1-531.e7.
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title = "Prevalence and correlates of mental health problems in prostate cancer survivors: A case control study comparing survivors with general population peers",
abstract = "ObjectiveThe purpose of this study was to identify factors associated with mental health (MH) problems in prostate cancer (PC) survivors. Toward this end, we evaluated (1) differences in the prevalence of MH problems between PC survivors and age-matched men from the general population (GenPop) and (2) correlates of MH in PC survivors and the GenPop.Methods and materialsIn this observational case-control study, we age-matched PC survivors (n = 644, alive≥5 y after diagnosis of a stage I–IV carcinoma) recruited from Dutch community hospitals (Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship registry) with GenPop peers (n = 644) selected from a population-based sample recruited in general practices (NIVEL). MH was operationalized using the 5-item Mental Health Inventory of the Short Form Health Survey (SF-36). Potential correlates of MH included sociodemographic characteristics, health-related quality of life scores, and clinical characteristics (PC survivors only). We used analysis of (co)variance and chi-square tests to address the 2 research questions.ResultsWe observed clinically relevant MH symptoms in 14{\%} of the PC survivors and 6{\%} of the GenPop controls (P<0.01, odds ratio = 2.45 [1.66–3.62]). The most important correlates of lower MH scores in the PC survivors were being widowed, a lower educational level, lower general health perceptions, more bodily pain and urinary bother, and less sexual satisfaction. The most important correlates of lower MH scores in the GenPop were as follows: lower general health perceptions, more role limitations because of physical problems, and more bodily pain.ConclusionsOur results indicate that long-term PC survivors have poorer MH, as assessed by the 5-item Mental Health Inventory questionnaire, than men of a comparable age from the GenPop without a history of PC. Attention to potentially modifiable factors associated with MH problems in PC survivors, such as urinary function and its related bother, bodily pain, and sexual satisfaction, may help to prevent or limit MH problems in this survivor population.",
author = "{van Stam}, M. and {van der Poel}, H.G. and J.L.H.R. Bosch and C.N. Tiller and S. Horenblas and F. Mols and N.K. Aaronson",
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Prevalence and correlates of mental health problems in prostate cancer survivors : A case control study comparing survivors with general population peers. / van Stam, M.; van der Poel, H.G.; Bosch, J.L.H.R.; Tiller, C.N.; Horenblas, S.; Mols, F.; Aaronson, N.K.

In: Urologic Oncology: Seminars and Original Investigations, Vol. 35, No. 8, 2017, p. 531.e1-531.e7.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Prevalence and correlates of mental health problems in prostate cancer survivors

T2 - A case control study comparing survivors with general population peers

AU - van Stam, M.

AU - van der Poel, H.G.

AU - Bosch, J.L.H.R.

AU - Tiller, C.N.

AU - Horenblas, S.

AU - Mols, F.

AU - Aaronson, N.K.

PY - 2017

Y1 - 2017

N2 - ObjectiveThe purpose of this study was to identify factors associated with mental health (MH) problems in prostate cancer (PC) survivors. Toward this end, we evaluated (1) differences in the prevalence of MH problems between PC survivors and age-matched men from the general population (GenPop) and (2) correlates of MH in PC survivors and the GenPop.Methods and materialsIn this observational case-control study, we age-matched PC survivors (n = 644, alive≥5 y after diagnosis of a stage I–IV carcinoma) recruited from Dutch community hospitals (Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship registry) with GenPop peers (n = 644) selected from a population-based sample recruited in general practices (NIVEL). MH was operationalized using the 5-item Mental Health Inventory of the Short Form Health Survey (SF-36). Potential correlates of MH included sociodemographic characteristics, health-related quality of life scores, and clinical characteristics (PC survivors only). We used analysis of (co)variance and chi-square tests to address the 2 research questions.ResultsWe observed clinically relevant MH symptoms in 14% of the PC survivors and 6% of the GenPop controls (P<0.01, odds ratio = 2.45 [1.66–3.62]). The most important correlates of lower MH scores in the PC survivors were being widowed, a lower educational level, lower general health perceptions, more bodily pain and urinary bother, and less sexual satisfaction. The most important correlates of lower MH scores in the GenPop were as follows: lower general health perceptions, more role limitations because of physical problems, and more bodily pain.ConclusionsOur results indicate that long-term PC survivors have poorer MH, as assessed by the 5-item Mental Health Inventory questionnaire, than men of a comparable age from the GenPop without a history of PC. Attention to potentially modifiable factors associated with MH problems in PC survivors, such as urinary function and its related bother, bodily pain, and sexual satisfaction, may help to prevent or limit MH problems in this survivor population.

AB - ObjectiveThe purpose of this study was to identify factors associated with mental health (MH) problems in prostate cancer (PC) survivors. Toward this end, we evaluated (1) differences in the prevalence of MH problems between PC survivors and age-matched men from the general population (GenPop) and (2) correlates of MH in PC survivors and the GenPop.Methods and materialsIn this observational case-control study, we age-matched PC survivors (n = 644, alive≥5 y after diagnosis of a stage I–IV carcinoma) recruited from Dutch community hospitals (Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship registry) with GenPop peers (n = 644) selected from a population-based sample recruited in general practices (NIVEL). MH was operationalized using the 5-item Mental Health Inventory of the Short Form Health Survey (SF-36). Potential correlates of MH included sociodemographic characteristics, health-related quality of life scores, and clinical characteristics (PC survivors only). We used analysis of (co)variance and chi-square tests to address the 2 research questions.ResultsWe observed clinically relevant MH symptoms in 14% of the PC survivors and 6% of the GenPop controls (P<0.01, odds ratio = 2.45 [1.66–3.62]). The most important correlates of lower MH scores in the PC survivors were being widowed, a lower educational level, lower general health perceptions, more bodily pain and urinary bother, and less sexual satisfaction. The most important correlates of lower MH scores in the GenPop were as follows: lower general health perceptions, more role limitations because of physical problems, and more bodily pain.ConclusionsOur results indicate that long-term PC survivors have poorer MH, as assessed by the 5-item Mental Health Inventory questionnaire, than men of a comparable age from the GenPop without a history of PC. Attention to potentially modifiable factors associated with MH problems in PC survivors, such as urinary function and its related bother, bodily pain, and sexual satisfaction, may help to prevent or limit MH problems in this survivor population.

U2 - 10.1016/j.urolonc.2017.03.028

DO - 10.1016/j.urolonc.2017.03.028

M3 - Article

VL - 35

SP - 531.e1-531.e7

JO - Urologic Oncology: Seminars and Original Investigations

JF - Urologic Oncology: Seminars and Original Investigations

SN - 1078-1439

IS - 8

ER -