Psychological and clinical characteristics of female patients with spontaneous coronary artery dissection

V.R. Smaardijk, P.M.C. Mommersteeg*, W.J. Kop, D. Adlam, A.H.E.M. Maas

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

5 Downloads (Pure)

Abstract

Aims
Spontaneous coronary artery dissection (SCAD) is increasingly recognised as a cause of myocardial infarction, but psychological characteristics of patients with SCAD have not yet been extensively investigated. We assessed the prevalence of a broad range of psychological and clinical factors, and their inter-relationships in patients with a history of SCAD. Furthermore, we investigated whether specific clusters of patients with SCAD can be identified.
Methods
Participants were recruited between March and May 2019 from a Dutch SCAD database and completed online questionnaires. Clinical information was verified by review of medical records. Participants were predominantly female (172/183; 94%). Analyses focused on the 172 female patients (mean age 52.0 ± 7.5 years, 37% postmenopausal).
Results
The most common comorbidities of SCAD were migraine (52%), fibromuscular dysplasia (FMD; 29%), chronic pain (29%), and tinnitus (28%). Six women (3%) had pregnancy-associated SCAD. Traditional cardiovascular risk factors were rare (<10%), except for hypertension (31%). Psychological assessment indicated high levels of perceived stress (PSS-10 ≥14; 50%), fatigue (FAS-10 ≥22; 56%), and a frequent history of burnout (25%). The prevalence of depression (9%) and anxiety (12%) was relatively low. Three clusters were identified: (A) FMD and chronic non-ischaemic conditions (tinnitus, chronic pain, and irritable bowel syndrome); (B) migraine; and (C) none of these conditions.
Conclusion
This study shows that perceived stress and fatigue are common in patients with SCAD, in addition to prevalent comorbid FMD, migraine, tinnitus, and non-ischaemic pain conditions. These factors may add to developing tailored rehabilitation programmes for patients with SCAD.
Original languageEnglish
Number of pages7
JournalNetherlands Heart Journal
DOIs
Publication statusE-pub ahead of print - 2020

Keywords

  • ANXIETY
  • ASSOCIATION
  • DEPRESSION
  • FATIGUE
  • Myocardial infarction
  • PREVALENCE
  • Risk factors
  • Spontaneous coronary artery dissection
  • Women

Fingerprint Dive into the research topics of 'Psychological and clinical characteristics of female patients with spontaneous coronary artery dissection'. Together they form a unique fingerprint.

  • Cite this