Psychological impact of lymphoma on adolescents and young adults: Not a matter of black or white

F.M. Drost, F. Mols, S.E. Kaal, W.B. Stevens, W.T. van der Graaf, J.B. Prins, O. Husson

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Abstract

The purpose of the study is to examine differences in perceived impact of cancer (IOC) between adolescents and young adults (AYAs; 18-35 years at cancer diagnosis), adults (36-64 years) and elderly (65-84 years) with a history of (non-)Hodgkin lymphoma. Furthermore, to investigate the association of socio-demographic, clinical and psychological characteristics with IOC; and the association between IOC and health-related quality of life (HRQoL) among AYAs only. This study is part of a population-based PROFILES registry survey among lymphoma patients diagnosed between 1999 and 2009. Patients (n = 1.281) were invited to complete the IOCv1 and EORTC-QLQ-C30 questionnaires. Response rate was 67 % (n = 861). AYA lymphoma survivors scored higher on the positive IOC summary scale, compared to adult and elderly patients (p <0.001), while no significant differences were observed for negative IOC. Among AYAs, females, survivors with a partner, and survivors with elevated psychological distress levels scored significantly higher on the negative IOC summary scale. The negative IOC summary scale was negatively associated with all EORTC QLQ-C30 functioning scales (beta ranging from -0.39 to -0.063; p <0.05). The positive IOC summary scale was negatively associated with the EORTC QLQ-C30 subscale 'Emotional functioning' (beta = -0.24; p <0.05). AYA, adult and elderly with a history of (non-)Hodgkin lymphoma experienced different types of IOC in terms of positive and negative aspects. Although AYAs experience a more positive IOC compared to older survivors, some AYAs experience more negative IOC and may require developmentally appropriate interventions to address their specific concerns.
Original languageEnglish
Pages (from-to)726-735
JournalJournal of Cancer Survivorship
Volume10
Issue number4
DOIs
Publication statusPublished - 2016

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Young Adult
Lymphoma
Neoplasms
Survivors
Non-Hodgkin's Lymphoma

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Drost, F. M., Mols, F., Kaal, S. E., Stevens, W. B., van der Graaf, W. T., Prins, J. B., & Husson, O. (2016). Psychological impact of lymphoma on adolescents and young adults: Not a matter of black or white. Journal of Cancer Survivorship, 10(4), 726-735. https://doi.org/10.1007/s11764-016-0518-7
Drost, F.M. ; Mols, F. ; Kaal, S.E. ; Stevens, W.B. ; van der Graaf, W.T. ; Prins, J.B. ; Husson, O. / Psychological impact of lymphoma on adolescents and young adults : Not a matter of black or white. In: Journal of Cancer Survivorship. 2016 ; Vol. 10, No. 4. pp. 726-735.
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abstract = "The purpose of the study is to examine differences in perceived impact of cancer (IOC) between adolescents and young adults (AYAs; 18-35 years at cancer diagnosis), adults (36-64 years) and elderly (65-84 years) with a history of (non-)Hodgkin lymphoma. Furthermore, to investigate the association of socio-demographic, clinical and psychological characteristics with IOC; and the association between IOC and health-related quality of life (HRQoL) among AYAs only. This study is part of a population-based PROFILES registry survey among lymphoma patients diagnosed between 1999 and 2009. Patients (n = 1.281) were invited to complete the IOCv1 and EORTC-QLQ-C30 questionnaires. Response rate was 67 {\%} (n = 861). AYA lymphoma survivors scored higher on the positive IOC summary scale, compared to adult and elderly patients (p <0.001), while no significant differences were observed for negative IOC. Among AYAs, females, survivors with a partner, and survivors with elevated psychological distress levels scored significantly higher on the negative IOC summary scale. The negative IOC summary scale was negatively associated with all EORTC QLQ-C30 functioning scales (beta ranging from -0.39 to -0.063; p <0.05). The positive IOC summary scale was negatively associated with the EORTC QLQ-C30 subscale 'Emotional functioning' (beta = -0.24; p <0.05). AYA, adult and elderly with a history of (non-)Hodgkin lymphoma experienced different types of IOC in terms of positive and negative aspects. Although AYAs experience a more positive IOC compared to older survivors, some AYAs experience more negative IOC and may require developmentally appropriate interventions to address their specific concerns.",
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Psychological impact of lymphoma on adolescents and young adults : Not a matter of black or white. / Drost, F.M.; Mols, F.; Kaal, S.E.; Stevens, W.B.; van der Graaf, W.T.; Prins, J.B.; Husson, O.

In: Journal of Cancer Survivorship, Vol. 10, No. 4, 2016, p. 726-735.

Research output: Contribution to journalArticleScientificpeer-review

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T2 - Not a matter of black or white

AU - Drost, F.M.

AU - Mols, F.

AU - Kaal, S.E.

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AU - van der Graaf, W.T.

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AU - Husson, O.

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N2 - The purpose of the study is to examine differences in perceived impact of cancer (IOC) between adolescents and young adults (AYAs; 18-35 years at cancer diagnosis), adults (36-64 years) and elderly (65-84 years) with a history of (non-)Hodgkin lymphoma. Furthermore, to investigate the association of socio-demographic, clinical and psychological characteristics with IOC; and the association between IOC and health-related quality of life (HRQoL) among AYAs only. This study is part of a population-based PROFILES registry survey among lymphoma patients diagnosed between 1999 and 2009. Patients (n = 1.281) were invited to complete the IOCv1 and EORTC-QLQ-C30 questionnaires. Response rate was 67 % (n = 861). AYA lymphoma survivors scored higher on the positive IOC summary scale, compared to adult and elderly patients (p <0.001), while no significant differences were observed for negative IOC. Among AYAs, females, survivors with a partner, and survivors with elevated psychological distress levels scored significantly higher on the negative IOC summary scale. The negative IOC summary scale was negatively associated with all EORTC QLQ-C30 functioning scales (beta ranging from -0.39 to -0.063; p <0.05). The positive IOC summary scale was negatively associated with the EORTC QLQ-C30 subscale 'Emotional functioning' (beta = -0.24; p <0.05). AYA, adult and elderly with a history of (non-)Hodgkin lymphoma experienced different types of IOC in terms of positive and negative aspects. Although AYAs experience a more positive IOC compared to older survivors, some AYAs experience more negative IOC and may require developmentally appropriate interventions to address their specific concerns.

AB - The purpose of the study is to examine differences in perceived impact of cancer (IOC) between adolescents and young adults (AYAs; 18-35 years at cancer diagnosis), adults (36-64 years) and elderly (65-84 years) with a history of (non-)Hodgkin lymphoma. Furthermore, to investigate the association of socio-demographic, clinical and psychological characteristics with IOC; and the association between IOC and health-related quality of life (HRQoL) among AYAs only. This study is part of a population-based PROFILES registry survey among lymphoma patients diagnosed between 1999 and 2009. Patients (n = 1.281) were invited to complete the IOCv1 and EORTC-QLQ-C30 questionnaires. Response rate was 67 % (n = 861). AYA lymphoma survivors scored higher on the positive IOC summary scale, compared to adult and elderly patients (p <0.001), while no significant differences were observed for negative IOC. Among AYAs, females, survivors with a partner, and survivors with elevated psychological distress levels scored significantly higher on the negative IOC summary scale. The negative IOC summary scale was negatively associated with all EORTC QLQ-C30 functioning scales (beta ranging from -0.39 to -0.063; p <0.05). The positive IOC summary scale was negatively associated with the EORTC QLQ-C30 subscale 'Emotional functioning' (beta = -0.24; p <0.05). AYA, adult and elderly with a history of (non-)Hodgkin lymphoma experienced different types of IOC in terms of positive and negative aspects. Although AYAs experience a more positive IOC compared to older survivors, some AYAs experience more negative IOC and may require developmentally appropriate interventions to address their specific concerns.

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JO - Journal of Cancer Survivorship

JF - Journal of Cancer Survivorship

SN - 1932-2259

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