@inproceedings{7b7950ecbb2a4687af9b9d1abf9a4de3,
title = "Psychopathic genes: A multi-level adaptive dynamic modelling approach",
abstract = "This paper investigates the role of epigenetics in the dynamics of psychopathy by designing and simulating a fifth-order multi-level adaptive network model. Understanding any disorder requires a comprehensive exploration of multiple dimensions. Therefore, this research proposes a computational model that takes into account (epi)genetic, neural, cognitive, and behavioural causal influences that generate psychopathic behaviour. It illustrates the impact of epigenetic influences on the genes MAO-A, 5-HTT, and OXTR and their consequences for other internal processes with regard to psychopathy. This paper includes a review of related literature in this research domain and the design and specifics of the adaptive network model addressing psychopathic behaviour. The model is evaluated by two simulations that show the difference in behaviour between individuals that at some point in their life develop psychopathy due to environmental circumstances and those not developing it. In addition, an extension of the model demonstrates the impact of cognitive behavioural therapy on an individual with psychopathy.",
keywords = "Psychopathy, Epigenetics, Multi-level, Adaptive Dynamic Modelling",
author = "Femke Augustinus and Hendrikse, \{Sophie C.F.\} and Jan Treur",
year = "2025",
month = jul,
doi = "10.1007/978-3-031-94770-4\_38",
language = "English",
isbn = "9783031947698",
volume = "4",
series = "Lecture notes in networks and systems ",
publisher = "Springer Nature",
pages = "477--498",
editor = "Radek Silhavy and Petr Silhavy",
booktitle = "System design in software engineering",
address = "United States",
edition = "1",
}