Psychosocial factors and the course of cervical intra-epithelial neoplasia: A prospective study

E.s.m. Tiersma; M.l. Van Der Lee; B. Garssen; A.a.w. Peters; A.p. Visser; G.j. Fleuren; K.m. Van Leeuwen; S. Le Cessie; K. Goodkin

doi:10.1016/j.ygyno.2005.03.003

Psychosocial factors and the course of cervical intra-epithelial neoplasia: A prospective study

E.s.m. Tiersma, M.l. Van Der Lee, B. Garssen, A.a.w. Peters, A.p. Visser, G.j. Fleuren, K.m. Van Leeuwen, S. Le Cessie, K. Goodkin

Research output: Contribution to journal › Article › Scientific › peer-review

Abstract

Objective.
To investigate the influence of psychosocial factors on the course of cervical intra-epithelial neoplasia (CIN).

Methods.
A group of 93 patients with CIN 1 or 2 was followed for 2.25 years by half-yearly colposcopy and cytology. Negatively-rated life events, social support, and coping style were studied in relation to distress during follow-up and in relation to time till progression and regression of CIN. Human papillomavirus (HPV) infection was controlled for as well as sick role bias caused by suspicion of having cervical cancer and distress due to the abnormal cervical smear.

Results.
During follow-up, progression was found in 20 patients (22%), stable disease in 22 patients (24%), and regression in 51 patients (55%). Negatively-rated life events and lack of social support predicted distress longitudinally. No association was found between progression or regression of CIN and negatively-rated life events, lack of social support, coping style, and distress.

Conclusion.
We found no evidence that psychosocial factors influence the course of CIN.

Original language	English
Pages (from-to)	879-886
Journal	Gynecologic Oncology
Volume	97
Issue number	3
DOIs	https://doi.org/10.1016/j.ygyno.2005.03.003
Publication status	Published - 2005
Externally published	Yes

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10.1016/j.ygyno.2005.03.003

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@article{68b5e452769f4ddd9c31bb17357a5d8d,

title = "Psychosocial factors and the course of cervical intra-epithelial neoplasia: A prospective study",

abstract = "Objective.To investigate the influence of psychosocial factors on the course of cervical intra-epithelial neoplasia (CIN).Methods.A group of 93 patients with CIN 1 or 2 was followed for 2.25 years by half-yearly colposcopy and cytology. Negatively-rated life events, social support, and coping style were studied in relation to distress during follow-up and in relation to time till progression and regression of CIN. Human papillomavirus (HPV) infection was controlled for as well as sick role bias caused by suspicion of having cervical cancer and distress due to the abnormal cervical smear.Results.During follow-up, progression was found in 20 patients (22%), stable disease in 22 patients (24%), and regression in 51 patients (55%). Negatively-rated life events and lack of social support predicted distress longitudinally. No association was found between progression or regression of CIN and negatively-rated life events, lack of social support, coping style, and distress.Conclusion.We found no evidence that psychosocial factors influence the course of CIN.",

author = "E.s.m. Tiersma and {Van Der Lee}, M.l. and B. Garssen and A.a.w. Peters and A.p. Visser and G.j. Fleuren and {Van Leeuwen}, K.m. and {Le Cessie}, S. and K. Goodkin",

year = "2005",

doi = "10.1016/j.ygyno.2005.03.003",

language = "English",

volume = "97",

pages = "879--886",

journal = "Gynecologic Oncology",

issn = "0090-8258",

publisher = "Academic Press Inc.",

number = "3",

}

TY - JOUR

T1 - Psychosocial factors and the course of cervical intra-epithelial neoplasia

T2 - A prospective study

AU - Tiersma, E.s.m.

AU - Van Der Lee, M.l.

AU - Garssen, B.

AU - Peters, A.a.w.

AU - Visser, A.p.

AU - Fleuren, G.j.

AU - Van Leeuwen, K.m.

AU - Le Cessie, S.

AU - Goodkin, K.

PY - 2005

Y1 - 2005

N2 - Objective.To investigate the influence of psychosocial factors on the course of cervical intra-epithelial neoplasia (CIN).Methods.A group of 93 patients with CIN 1 or 2 was followed for 2.25 years by half-yearly colposcopy and cytology. Negatively-rated life events, social support, and coping style were studied in relation to distress during follow-up and in relation to time till progression and regression of CIN. Human papillomavirus (HPV) infection was controlled for as well as sick role bias caused by suspicion of having cervical cancer and distress due to the abnormal cervical smear.Results.During follow-up, progression was found in 20 patients (22%), stable disease in 22 patients (24%), and regression in 51 patients (55%). Negatively-rated life events and lack of social support predicted distress longitudinally. No association was found between progression or regression of CIN and negatively-rated life events, lack of social support, coping style, and distress.Conclusion.We found no evidence that psychosocial factors influence the course of CIN.

AB - Objective.To investigate the influence of psychosocial factors on the course of cervical intra-epithelial neoplasia (CIN).Methods.A group of 93 patients with CIN 1 or 2 was followed for 2.25 years by half-yearly colposcopy and cytology. Negatively-rated life events, social support, and coping style were studied in relation to distress during follow-up and in relation to time till progression and regression of CIN. Human papillomavirus (HPV) infection was controlled for as well as sick role bias caused by suspicion of having cervical cancer and distress due to the abnormal cervical smear.Results.During follow-up, progression was found in 20 patients (22%), stable disease in 22 patients (24%), and regression in 51 patients (55%). Negatively-rated life events and lack of social support predicted distress longitudinally. No association was found between progression or regression of CIN and negatively-rated life events, lack of social support, coping style, and distress.Conclusion.We found no evidence that psychosocial factors influence the course of CIN.

U2 - 10.1016/j.ygyno.2005.03.003

DO - 10.1016/j.ygyno.2005.03.003

M3 - Article

SN - 0090-8258

VL - 97

SP - 879

EP - 886

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 3

ER -

Psychosocial factors and the course of cervical intra-epithelial neoplasia: A prospective study

Abstract

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