Quality of life after young ischemic stroke of mild severity is mainly influenced by psychological factors

M. de Bruijn, N.A. Synhaeve, M.W.A. van Rijsbergen, F.-E. de Leeuw, R.E. Mark, B. Jansen, P.L. de Kort

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background
Long-term prognosis in terms of quality of life (QoL) in young stroke patients is of importance because they usually have a long life expectancy and extensive daily life demands. We aimed at determining which medical and psychological factors influence the QoL in young stroke patients (<50 years), after long-term follow-up.
Methods
Young ischemic stroke patients admitted to the St. Elisabeth Hospital and the TweeSteden Hospital, Tilburg, the Netherlands, between 2000 and 2010 were included. One hundred seventy patients and 61 controls filled out the following questionnaires: (1) the Hospital Anxiety and Depression Scale, (2) the Fatigue Assessment Scale, and (3) the shortened World Health Organization Quality of Life scale. Using linear multiple regression analysis, we assessed the factors influencing QoL.ResultsQoL did not differ significantly between patients (median modified Rankin Scale score at follow-up, 0) and controls after a mean follow-up of 4.5 (standard deviation, 2.8) years. The presence of excessive fatigue was associated with lower scores on all domains of the QoL (P ≤ .003), but not for general health domain (P = .010). Similarly, depression was associated with worse QoL on the physical (P = .004) and psychological (P = .001) domains and anxiety with lower scores on the psychological (P < .001) QoL domain. No relationship was found between stroke-specific factors and QoL.
Conclusions
Fatigue and to a lesser extent depression and anxiety affect the QoL in young adults after ischemic stroke of mild severity. Therefore, young stroke patients should be informed about, screened, and, if possible, treated for fatigue, depression, and anxiety.Keywords: Young stroke, prognosis, quality of life, fatigue
Original languageEnglish
Pages (from-to)2183-2188
JournalJournal of Stroke and Cerebrovascular Diseases
Volume24
Issue number10
DOIs
Publication statusPublished - 2015

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Depression
Life Expectancy
Netherlands
Young Adult
Linear Models
Surveys and Questionnaires

Cite this

de Bruijn, M. ; Synhaeve, N.A. ; van Rijsbergen, M.W.A. ; de Leeuw, F.-E. ; Mark, R.E. ; Jansen, B. ; de Kort, P.L. / Quality of life after young ischemic stroke of mild severity is mainly influenced by psychological factors. In: Journal of Stroke and Cerebrovascular Diseases. 2015 ; Vol. 24, No. 10. pp. 2183-2188.
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title = "Quality of life after young ischemic stroke of mild severity is mainly influenced by psychological factors",
abstract = "BackgroundLong-term prognosis in terms of quality of life (QoL) in young stroke patients is of importance because they usually have a long life expectancy and extensive daily life demands. We aimed at determining which medical and psychological factors influence the QoL in young stroke patients (<50 years), after long-term follow-up.MethodsYoung ischemic stroke patients admitted to the St. Elisabeth Hospital and the TweeSteden Hospital, Tilburg, the Netherlands, between 2000 and 2010 were included. One hundred seventy patients and 61 controls filled out the following questionnaires: (1) the Hospital Anxiety and Depression Scale, (2) the Fatigue Assessment Scale, and (3) the shortened World Health Organization Quality of Life scale. Using linear multiple regression analysis, we assessed the factors influencing QoL.ResultsQoL did not differ significantly between patients (median modified Rankin Scale score at follow-up, 0) and controls after a mean follow-up of 4.5 (standard deviation, 2.8) years. The presence of excessive fatigue was associated with lower scores on all domains of the QoL (P ≤ .003), but not for general health domain (P = .010). Similarly, depression was associated with worse QoL on the physical (P = .004) and psychological (P = .001) domains and anxiety with lower scores on the psychological (P < .001) QoL domain. No relationship was found between stroke-specific factors and QoL.ConclusionsFatigue and to a lesser extent depression and anxiety affect the QoL in young adults after ischemic stroke of mild severity. Therefore, young stroke patients should be informed about, screened, and, if possible, treated for fatigue, depression, and anxiety.Keywords: Young stroke, prognosis, quality of life, fatigue",
author = "{de Bruijn}, M. and N.A. Synhaeve and {van Rijsbergen}, M.W.A. and {de Leeuw}, F.-E. and R.E. Mark and B. Jansen and {de Kort}, P.L.",
year = "2015",
doi = "10.1016/j.jstrokecerebrovasdis.2015.04.040",
language = "English",
volume = "24",
pages = "2183--2188",
journal = "Journal of Stroke and Cerebrovascular Diseases",
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Quality of life after young ischemic stroke of mild severity is mainly influenced by psychological factors. / de Bruijn, M.; Synhaeve, N.A.; van Rijsbergen, M.W.A.; de Leeuw, F.-E.; Mark, R.E.; Jansen, B.; de Kort, P.L.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 24, No. 10, 2015, p. 2183-2188.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Quality of life after young ischemic stroke of mild severity is mainly influenced by psychological factors

AU - de Bruijn, M.

AU - Synhaeve, N.A.

AU - van Rijsbergen, M.W.A.

AU - de Leeuw, F.-E.

AU - Mark, R.E.

AU - Jansen, B.

AU - de Kort, P.L.

PY - 2015

Y1 - 2015

N2 - BackgroundLong-term prognosis in terms of quality of life (QoL) in young stroke patients is of importance because they usually have a long life expectancy and extensive daily life demands. We aimed at determining which medical and psychological factors influence the QoL in young stroke patients (<50 years), after long-term follow-up.MethodsYoung ischemic stroke patients admitted to the St. Elisabeth Hospital and the TweeSteden Hospital, Tilburg, the Netherlands, between 2000 and 2010 were included. One hundred seventy patients and 61 controls filled out the following questionnaires: (1) the Hospital Anxiety and Depression Scale, (2) the Fatigue Assessment Scale, and (3) the shortened World Health Organization Quality of Life scale. Using linear multiple regression analysis, we assessed the factors influencing QoL.ResultsQoL did not differ significantly between patients (median modified Rankin Scale score at follow-up, 0) and controls after a mean follow-up of 4.5 (standard deviation, 2.8) years. The presence of excessive fatigue was associated with lower scores on all domains of the QoL (P ≤ .003), but not for general health domain (P = .010). Similarly, depression was associated with worse QoL on the physical (P = .004) and psychological (P = .001) domains and anxiety with lower scores on the psychological (P < .001) QoL domain. No relationship was found between stroke-specific factors and QoL.ConclusionsFatigue and to a lesser extent depression and anxiety affect the QoL in young adults after ischemic stroke of mild severity. Therefore, young stroke patients should be informed about, screened, and, if possible, treated for fatigue, depression, and anxiety.Keywords: Young stroke, prognosis, quality of life, fatigue

AB - BackgroundLong-term prognosis in terms of quality of life (QoL) in young stroke patients is of importance because they usually have a long life expectancy and extensive daily life demands. We aimed at determining which medical and psychological factors influence the QoL in young stroke patients (<50 years), after long-term follow-up.MethodsYoung ischemic stroke patients admitted to the St. Elisabeth Hospital and the TweeSteden Hospital, Tilburg, the Netherlands, between 2000 and 2010 were included. One hundred seventy patients and 61 controls filled out the following questionnaires: (1) the Hospital Anxiety and Depression Scale, (2) the Fatigue Assessment Scale, and (3) the shortened World Health Organization Quality of Life scale. Using linear multiple regression analysis, we assessed the factors influencing QoL.ResultsQoL did not differ significantly between patients (median modified Rankin Scale score at follow-up, 0) and controls after a mean follow-up of 4.5 (standard deviation, 2.8) years. The presence of excessive fatigue was associated with lower scores on all domains of the QoL (P ≤ .003), but not for general health domain (P = .010). Similarly, depression was associated with worse QoL on the physical (P = .004) and psychological (P = .001) domains and anxiety with lower scores on the psychological (P < .001) QoL domain. No relationship was found between stroke-specific factors and QoL.ConclusionsFatigue and to a lesser extent depression and anxiety affect the QoL in young adults after ischemic stroke of mild severity. Therefore, young stroke patients should be informed about, screened, and, if possible, treated for fatigue, depression, and anxiety.Keywords: Young stroke, prognosis, quality of life, fatigue

U2 - 10.1016/j.jstrokecerebrovasdis.2015.04.040

DO - 10.1016/j.jstrokecerebrovasdis.2015.04.040

M3 - Article

VL - 24

SP - 2183

EP - 2188

JO - Journal of Stroke and Cerebrovascular Diseases

JF - Journal of Stroke and Cerebrovascular Diseases

SN - 1052-3057

IS - 10

ER -