Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

F.C.L. Donkers, Z.A. Englander, P.H.E. Tiesinga, K.M. Cleary, H. Gu, A. Belger

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background
Event-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.
Methods
In 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.
Results
Patients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.
Conclusions
These results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.
Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency band
Theta frequency band
Gamma frequency band
P3
Original languageEnglish
Pages (from-to)266-268
JournalSchizophrenia Research
Volume150
Issue number1
DOIs
Publication statusPublished - 2013

Fingerprint

Electroencephalography
Efficiency

Cite this

Donkers, F. C. L., Englander, Z. A., Tiesinga, P. H. E., Cleary, K. M., Gu, H., & Belger, A. (2013). Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia. Schizophrenia Research, 150(1), 266-268. https://doi.org/10.1016/j.schres.2013.07.050
Donkers, F.C.L. ; Englander, Z.A. ; Tiesinga, P.H.E. ; Cleary, K.M. ; Gu, H. ; Belger, A. / Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia. In: Schizophrenia Research. 2013 ; Vol. 150, No. 1. pp. 266-268.
@article{5eb0ef9192b84b5f91f811b7aaff47cd,
title = "Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia",
abstract = "BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3",
author = "F.C.L. Donkers and Z.A. Englander and P.H.E. Tiesinga and K.M. Cleary and H. Gu and A. Belger",
year = "2013",
doi = "10.1016/j.schres.2013.07.050",
language = "English",
volume = "150",
pages = "266--268",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier",
number = "1",

}

Donkers, FCL, Englander, ZA, Tiesinga, PHE, Cleary, KM, Gu, H & Belger, A 2013, 'Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia', Schizophrenia Research, vol. 150, no. 1, pp. 266-268. https://doi.org/10.1016/j.schres.2013.07.050

Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia. / Donkers, F.C.L.; Englander, Z.A.; Tiesinga, P.H.E.; Cleary, K.M.; Gu, H.; Belger, A.

In: Schizophrenia Research, Vol. 150, No. 1, 2013, p. 266-268.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

AU - Donkers, F.C.L.

AU - Englander, Z.A.

AU - Tiesinga, P.H.E.

AU - Cleary, K.M.

AU - Gu, H.

AU - Belger, A.

PY - 2013

Y1 - 2013

N2 - BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3

AB - BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3

U2 - 10.1016/j.schres.2013.07.050

DO - 10.1016/j.schres.2013.07.050

M3 - Article

VL - 150

SP - 266

EP - 268

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

IS - 1

ER -