Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

F.C.L. Donkers; Z.A. Englander; P.H.E. Tiesinga; K.M. Cleary; H. Gu; A. Belger

doi:10.1016/j.schres.2013.07.050

Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

F.C.L. Donkers, Z.A. Englander, P.H.E. Tiesinga, K.M. Cleary, H. Gu, A. Belger

Developmental Psychology

Research output: Contribution to journal › Article › Scientific › peer-review

9 Citations (Scopus)

Abstract

Background
Event-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.
Methods
In 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.
Results
Patients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.
Conclusions
These results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.
Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency band
Theta frequency band
Gamma frequency band
P3

Original language	English
Pages (from-to)	266-268
Journal	Schizophrenia Research
Volume	150
Issue number	1
DOIs	https://doi.org/10.1016/j.schres.2013.07.050
Publication status	Published - 2013

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title = "Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia",

abstract = "BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3",

author = "F.C.L. Donkers and Z.A. Englander and P.H.E. Tiesinga and K.M. Cleary and H. Gu and A. Belger",

year = "2013",

doi = "10.1016/j.schres.2013.07.050",

language = "English",

volume = "150",

pages = "266--268",

journal = "Schizophrenia Research",

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T1 - Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

AU - Donkers, F.C.L.

AU - Englander, Z.A.

AU - Tiesinga, P.H.E.

AU - Cleary, K.M.

AU - Gu, H.

AU - Belger, A.

PY - 2013

Y1 - 2013

N2 - BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3

AB - BackgroundEvent-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.MethodsIn 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.ResultsPatients showed reductions in P3 amplitude accompanied by reduced low frequency delta–theta and increased beta–gamma band EEG activity.ConclusionsThese results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.Keywords: Schizophrenia, Wavelet analysis, Time–frequency analysis, Delta frequency bandTheta frequency bandGamma frequency bandP3

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DO - 10.1016/j.schres.2013.07.050

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VL - 150

SP - 266

EP - 268

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

IS - 1

ER -

Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

Abstract

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