Screening op aneurysma aortae abdominalis: Effectiviteit en kosteneffectiviteit

Translated title of the contribution: Screening for abdominal aortic aneurysm; effectivity and cost-effectiveness

Paul F van Gils, G Ardine de Wit, A.J. Schuit, Matthijs van den Berg

Research output: Contribution to journalReview articleScientificpeer-review

1 Citation (Scopus)
26 Downloads (Pure)

Abstract

Objective:

To review the current literature concerning the effectivity and cost-effectiveness of screening for abdominal aortic aneurysm (AAA).

Design:

Systematic review.

Method:

A review of literature of evaluations of effectivity via meta-analyses and economic evaluations.

Results:

The short-term meta-analyses showed that screening for AAA leads to a significant reduction of AAA-related mortality. The average absolute risk reduction (ARR) was 0.12%. The long-term meta-analysis also showed a significant reduction of overall mortality. The ARR was in this case almost 1%. The five economic evaluations all resulted in cost-effectiveness ratios below euro 20,000 per quality-adjusted life year (QALY), a used threshold level in the Netherlands.

Conclusion:

Based on the available literature, screening for AAA has appeared to be both effective and cost-effective. However, the economic evaluations did not always take into account the peri- and post-operative mortality and morbidity. Economic evaluations are only useful if all possible outcomes are included in the model. Therefore a good model analysis should be made for the Dutch situation, after which a decision may be taken on a possible pilot study and the optimal design thereof.

Translated title of the contributionScreening for abdominal aortic aneurysm; effectivity and cost-effectiveness
Original languageDutch
Article numberB383
JournalNederlandsch Tijdschrift voor Geneeskunde
Volume153
Publication statusPublished - 2009
Externally publishedYes

Keywords

  • Aortic Aneurysm, Abdominal
  • Aortic Rupture
  • Cost-Benefit Analysis
  • Humans
  • Life Expectancy
  • Mass Screening
  • Risk Assessment
  • Risk Factors
  • English Abstract
  • Journal Article
  • Meta-Analysis
  • Review

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