Screening instruments to detect problematic alcohol use among adults in hospitals and their diagnostic test accuracy: A systematic review

J.M. Bisschop*, H.J.M. de Jonge, A.H. Brunsveld-Reinders, H. van de Mheen, J.J.P. Mathijssen, A.D. Rozema

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Issues
Alcohol consumption can cause physical, psychological and social problems that can result in hospitalisations. Screening in hospitals helps to determine which patients should be given interventions. In this review, we aimed to summarise the diagnostic test accuracy (DTA) of screening instruments for problematic alcohol use among adults in hospitals.

Approach
We searched three databases for studies that assessed validated screening instruments for problematic alcohol use among hospitalised adults. We used the Quality Assessment of Diagnostic Accuracy Studies 2 tool to evaluate the risk of bias.

Key Findings
We included 20 studies in the review. In 11 studies performed in the emergency departments, 5 instruments had a high DTA: the AUDIT, the AUDIT-C, the RAPS4-QF, the 2-question screener and HOLD 5. In the eight studies with inpatients, three instruments had a high DTA: the AUDIT, CAGE-C and CAGE +10 items. Finally, only one of the included studies evaluated outpatients; the authors reported a high DTA for the AUDIT-C.

Implication and Conclusions
The results indicate that the AUDIT is an appropriate screening instrument for both inpatients and patients in the emergency department. Moreover, for patients in the emergency department, the AUDIT-C and the RAPS4-QF can be used. More research is needed on outpatients, and several screening instruments have only been validated with one study (i.e., the 2-question screener, DSM-IV-2, HOLD 5, CAGE-C and CAGE +10 questions).
Original languageEnglish
Pages (from-to)505-531
JournalDrug and Alcohol Review
Volume44
Issue number2
DOIs
Publication statusPublished - 2025

Keywords

  • adults
  • alcohol use disorder
  • hospital
  • problematic alcohol use
  • screening instrument

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