Serotonin, Predictive Processing and Psychedelics

Research output: Contribution to journalArticleScientificpeer-review


Letheby’s "Philosophy of Psychedelics" relies on Predictive Processing to try and find unifying explanations relevant to understanding how serotonergic psychedelics work in psychiatric therapy, what subjective experiences are associated with their use and whether such experiences are epistemically defective. But if Predictive Processing lacks genuinely explanatory unifying power, Letheby’s account of psychedelic therapy risks being unwarranted. In this commentary, I motivate this worry and sketch an alternative interpretation of psychedelic therapy within the Reinforcement Learning framework.
Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalPhilosophy and the Mind Sciences
Issue number7
Publication statusPublished - 19 Apr 2022


  • Predictive Processing
  • Reinforcement Learning
  • Unification


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