The effect of spiritual interventions on quality of life of cancer patients:

a systematic review and meta-analysis

Research output: Contribution to journalArticleScientificpeer-review

Abstract

OBJECTIVE:
The aim of this study was to examine the effect of spiritual interventions on quality of life of cancer patients.

METHODS:
We conducted our search on June 6, 2014 in Medline, PsycINFO, Embase, and PubMed. All clinical trials were included that compared standard care with a spiritual intervention that addressed existential themes using a narrative approach. Study quality was evaluated by the Cochrane Risk of Bias Tool.

RESULTS:
A total of 4972 studies were identified, of which 14 clinical trials (2050 patients) met the inclusion criteria, and 12 trials (1878 patients) were included in the meta-analysis. The overall risk of bias was high. When combined, all studies showed a moderate effect (d) 0.50 (95% CI = 0.20-0.79) 0-2 weeks after the intervention on overall quality of life in favor of the spiritual interventions. Meta-analysis at 3-6 months after the intervention showed a small insignificant effect (0.14, 95% CI = -0.08 to 0.35). Subgroup analysis including only the western studies showed a small effect of 0.17 (95% CI = 0.05-0.29). Including only studies that met the allocation concealment criteria showed an insignificant effect of 0.14 (95% CI = -0.05 to 0.33).

CONCLUSIONS:
Directly after the intervention, spiritual interventions had a moderate beneficial effect in terms of improving quality of life of cancer patients compared with that of a control group. No evidence was found that the interventions maintained this effect up to 3-6 months after the intervention. Further research is needed to understand how spiritual interventions could contribute to a long-term effect of increasing or maintaining quality of life.
Original languageEnglish
Pages (from-to)253-265
JournalPsycho-Oncology: Journal of the psychological, social and behavioral dimensions of cancer
Volume25
Issue number3
Publication statusPublished - 10 Aug 2015
Externally publishedYes

Fingerprint

Neoplasms
PubMed

Cite this

@article{f612f52a545b48c6b878a0eef9867ca5,
title = "The effect of spiritual interventions on quality of life of cancer patients:: a systematic review and meta-analysis",
abstract = "OBJECTIVE:The aim of this study was to examine the effect of spiritual interventions on quality of life of cancer patients.METHODS:We conducted our search on June 6, 2014 in Medline, PsycINFO, Embase, and PubMed. All clinical trials were included that compared standard care with a spiritual intervention that addressed existential themes using a narrative approach. Study quality was evaluated by the Cochrane Risk of Bias Tool.RESULTS:A total of 4972 studies were identified, of which 14 clinical trials (2050 patients) met the inclusion criteria, and 12 trials (1878 patients) were included in the meta-analysis. The overall risk of bias was high. When combined, all studies showed a moderate effect (d) 0.50 (95{\%} CI = 0.20-0.79) 0-2 weeks after the intervention on overall quality of life in favor of the spiritual interventions. Meta-analysis at 3-6 months after the intervention showed a small insignificant effect (0.14, 95{\%} CI = -0.08 to 0.35). Subgroup analysis including only the western studies showed a small effect of 0.17 (95{\%} CI = 0.05-0.29). Including only studies that met the allocation concealment criteria showed an insignificant effect of 0.14 (95{\%} CI = -0.05 to 0.33).CONCLUSIONS:Directly after the intervention, spiritual interventions had a moderate beneficial effect in terms of improving quality of life of cancer patients compared with that of a control group. No evidence was found that the interventions maintained this effect up to 3-6 months after the intervention. Further research is needed to understand how spiritual interventions could contribute to a long-term effect of increasing or maintaining quality of life.",
author = "Renske Kruizinga",
year = "2015",
month = "8",
day = "10",
language = "English",
volume = "25",
pages = "253--265",
journal = "Psycho-Oncology",
issn = "1057-9249",
publisher = "Wiley",
number = "3",

}

TY - JOUR

T1 - The effect of spiritual interventions on quality of life of cancer patients:

T2 - a systematic review and meta-analysis

AU - Kruizinga, Renske

PY - 2015/8/10

Y1 - 2015/8/10

N2 - OBJECTIVE:The aim of this study was to examine the effect of spiritual interventions on quality of life of cancer patients.METHODS:We conducted our search on June 6, 2014 in Medline, PsycINFO, Embase, and PubMed. All clinical trials were included that compared standard care with a spiritual intervention that addressed existential themes using a narrative approach. Study quality was evaluated by the Cochrane Risk of Bias Tool.RESULTS:A total of 4972 studies were identified, of which 14 clinical trials (2050 patients) met the inclusion criteria, and 12 trials (1878 patients) were included in the meta-analysis. The overall risk of bias was high. When combined, all studies showed a moderate effect (d) 0.50 (95% CI = 0.20-0.79) 0-2 weeks after the intervention on overall quality of life in favor of the spiritual interventions. Meta-analysis at 3-6 months after the intervention showed a small insignificant effect (0.14, 95% CI = -0.08 to 0.35). Subgroup analysis including only the western studies showed a small effect of 0.17 (95% CI = 0.05-0.29). Including only studies that met the allocation concealment criteria showed an insignificant effect of 0.14 (95% CI = -0.05 to 0.33).CONCLUSIONS:Directly after the intervention, spiritual interventions had a moderate beneficial effect in terms of improving quality of life of cancer patients compared with that of a control group. No evidence was found that the interventions maintained this effect up to 3-6 months after the intervention. Further research is needed to understand how spiritual interventions could contribute to a long-term effect of increasing or maintaining quality of life.

AB - OBJECTIVE:The aim of this study was to examine the effect of spiritual interventions on quality of life of cancer patients.METHODS:We conducted our search on June 6, 2014 in Medline, PsycINFO, Embase, and PubMed. All clinical trials were included that compared standard care with a spiritual intervention that addressed existential themes using a narrative approach. Study quality was evaluated by the Cochrane Risk of Bias Tool.RESULTS:A total of 4972 studies were identified, of which 14 clinical trials (2050 patients) met the inclusion criteria, and 12 trials (1878 patients) were included in the meta-analysis. The overall risk of bias was high. When combined, all studies showed a moderate effect (d) 0.50 (95% CI = 0.20-0.79) 0-2 weeks after the intervention on overall quality of life in favor of the spiritual interventions. Meta-analysis at 3-6 months after the intervention showed a small insignificant effect (0.14, 95% CI = -0.08 to 0.35). Subgroup analysis including only the western studies showed a small effect of 0.17 (95% CI = 0.05-0.29). Including only studies that met the allocation concealment criteria showed an insignificant effect of 0.14 (95% CI = -0.05 to 0.33).CONCLUSIONS:Directly after the intervention, spiritual interventions had a moderate beneficial effect in terms of improving quality of life of cancer patients compared with that of a control group. No evidence was found that the interventions maintained this effect up to 3-6 months after the intervention. Further research is needed to understand how spiritual interventions could contribute to a long-term effect of increasing or maintaining quality of life.

M3 - Article

VL - 25

SP - 253

EP - 265

JO - Psycho-Oncology

JF - Psycho-Oncology

SN - 1057-9249

IS - 3

ER -