The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset

M. Cuypers, R. Lamers, E.B. Cornel, L.V. van de Poll-Franse, M. de Vries, P.J.M. Kil

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Abstract

Objective:
The objective of this study is to test if patients' health-related quality of life (HRQoL) declines after prostate biopsy to detect Pca, and after subsequent treatment decision-making in case Pca is confirmed, and to test whether personality state and traits are associated with these potential changes in HRQoL.
Methods:
Patients who were scheduled for prostate biopsy to detect Pca (N = 377) filled out a baseline questionnaire about HRQoL (EORTC QLQ-C30 and PR25), "big five" personality traits (BFI-10), optimism (LOT-r), and self-efficacy (Decision Self-efficacy Scale) (t0). Patients with confirmed Pca (N = 126) filled out a follow-up questionnaire on HRQoL within 2 weeks after treatment was chosen but had not yet started (t1).
Results:
HRQoL declined between t0 and t1, reflected in impaired role and cognitive functioning, and elevated fatigue, constipation, and prostate-specific symptoms. Sexual activity and functioning improved. Baseline HRQoL scores were unrelated to the selection of a particular treatment, but for patients who chose a curative treatment, post-decision HRQoL showed a greater decline compared to patients who chose active surveillance. Optimism was associated with HRQoL at baseline; decisional self-efficacy was positively associated with HRQoL at follow-up. No associations between HRQoL and the "big five" personality traits were found.
Conclusion:
Patients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making
Original languageEnglish
Pages (from-to)1297-1304
JournalSupportive Care in Cancer
Volume26
Issue number4
DOIs
Publication statusPublished - 2018

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Constipation
Optimism
Surveys and Questionnaires

Keywords

  • ACTIVE SURVEILLANCE
  • Cancer
  • DISTRESS
  • Decision-making
  • Decisional self-efficacy
  • Diagnosis
  • HRQoL
  • MEN
  • OLDER AMERICANS
  • Oncology
  • Optimism
  • PERSONALITY
  • Prostate cancer
  • SURVIVORS
  • THREAT
  • URINARY

Cite this

@article{5958d4963d5d43d6b4c15d23d8a97531,
title = "The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset",
abstract = "Objective: The objective of this study is to test if patients' health-related quality of life (HRQoL) declines after prostate biopsy to detect Pca, and after subsequent treatment decision-making in case Pca is confirmed, and to test whether personality state and traits are associated with these potential changes in HRQoL.Methods: Patients who were scheduled for prostate biopsy to detect Pca (N = 377) filled out a baseline questionnaire about HRQoL (EORTC QLQ-C30 and PR25), {"}big five{"} personality traits (BFI-10), optimism (LOT-r), and self-efficacy (Decision Self-efficacy Scale) (t0). Patients with confirmed Pca (N = 126) filled out a follow-up questionnaire on HRQoL within 2 weeks after treatment was chosen but had not yet started (t1).Results: HRQoL declined between t0 and t1, reflected in impaired role and cognitive functioning, and elevated fatigue, constipation, and prostate-specific symptoms. Sexual activity and functioning improved. Baseline HRQoL scores were unrelated to the selection of a particular treatment, but for patients who chose a curative treatment, post-decision HRQoL showed a greater decline compared to patients who chose active surveillance. Optimism was associated with HRQoL at baseline; decisional self-efficacy was positively associated with HRQoL at follow-up. No associations between HRQoL and the {"}big five{"} personality traits were found.Conclusion: Patients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making",
keywords = "ACTIVE SURVEILLANCE, Cancer, DISTRESS, Decision-making, Decisional self-efficacy, Diagnosis, HRQoL, MEN, OLDER AMERICANS, Oncology, Optimism, PERSONALITY, Prostate cancer, SURVIVORS, THREAT, URINARY",
author = "M. Cuypers and R. Lamers and E.B. Cornel and {van de Poll-Franse}, L.V. and {de Vries}, M. and P.J.M. Kil",
year = "2018",
doi = "10.1007/s00520-017-3953-8",
language = "English",
volume = "26",
pages = "1297--1304",
journal = "Supportive Care in Cancer",
issn = "0941-4355",
publisher = "Springer",
number = "4",

}

The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset. / Cuypers, M.; Lamers, R.; Cornel, E.B.; van de Poll-Franse, L.V.; de Vries, M.; Kil, P.J.M.

In: Supportive Care in Cancer, Vol. 26, No. 4, 2018, p. 1297-1304.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset

AU - Cuypers, M.

AU - Lamers, R.

AU - Cornel, E.B.

AU - van de Poll-Franse, L.V.

AU - de Vries, M.

AU - Kil, P.J.M.

PY - 2018

Y1 - 2018

N2 - Objective: The objective of this study is to test if patients' health-related quality of life (HRQoL) declines after prostate biopsy to detect Pca, and after subsequent treatment decision-making in case Pca is confirmed, and to test whether personality state and traits are associated with these potential changes in HRQoL.Methods: Patients who were scheduled for prostate biopsy to detect Pca (N = 377) filled out a baseline questionnaire about HRQoL (EORTC QLQ-C30 and PR25), "big five" personality traits (BFI-10), optimism (LOT-r), and self-efficacy (Decision Self-efficacy Scale) (t0). Patients with confirmed Pca (N = 126) filled out a follow-up questionnaire on HRQoL within 2 weeks after treatment was chosen but had not yet started (t1).Results: HRQoL declined between t0 and t1, reflected in impaired role and cognitive functioning, and elevated fatigue, constipation, and prostate-specific symptoms. Sexual activity and functioning improved. Baseline HRQoL scores were unrelated to the selection of a particular treatment, but for patients who chose a curative treatment, post-decision HRQoL showed a greater decline compared to patients who chose active surveillance. Optimism was associated with HRQoL at baseline; decisional self-efficacy was positively associated with HRQoL at follow-up. No associations between HRQoL and the "big five" personality traits were found.Conclusion: Patients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making

AB - Objective: The objective of this study is to test if patients' health-related quality of life (HRQoL) declines after prostate biopsy to detect Pca, and after subsequent treatment decision-making in case Pca is confirmed, and to test whether personality state and traits are associated with these potential changes in HRQoL.Methods: Patients who were scheduled for prostate biopsy to detect Pca (N = 377) filled out a baseline questionnaire about HRQoL (EORTC QLQ-C30 and PR25), "big five" personality traits (BFI-10), optimism (LOT-r), and self-efficacy (Decision Self-efficacy Scale) (t0). Patients with confirmed Pca (N = 126) filled out a follow-up questionnaire on HRQoL within 2 weeks after treatment was chosen but had not yet started (t1).Results: HRQoL declined between t0 and t1, reflected in impaired role and cognitive functioning, and elevated fatigue, constipation, and prostate-specific symptoms. Sexual activity and functioning improved. Baseline HRQoL scores were unrelated to the selection of a particular treatment, but for patients who chose a curative treatment, post-decision HRQoL showed a greater decline compared to patients who chose active surveillance. Optimism was associated with HRQoL at baseline; decisional self-efficacy was positively associated with HRQoL at follow-up. No associations between HRQoL and the "big five" personality traits were found.Conclusion: Patients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making

KW - ACTIVE SURVEILLANCE

KW - Cancer

KW - DISTRESS

KW - Decision-making

KW - Decisional self-efficacy

KW - Diagnosis

KW - HRQoL

KW - MEN

KW - OLDER AMERICANS

KW - Oncology

KW - Optimism

KW - PERSONALITY

KW - Prostate cancer

KW - SURVIVORS

KW - THREAT

KW - URINARY

U2 - 10.1007/s00520-017-3953-8

DO - 10.1007/s00520-017-3953-8

M3 - Article

VL - 26

SP - 1297

EP - 1304

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

SN - 0941-4355

IS - 4

ER -