Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands

L. N. van Steenbergen, A. C. Voogd, J. A. Roukema, W. J. Louwman, L. E. M. Duijm, J. W. W. Coebergh, L. van de Poll-Franse

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background
To examine variation in time and place in axillary staging and treatment of patients with ductal carcinoma in situ (DCIS) of the breast.
Methods
Trends in patients with DCIS recorded in the Eindhoven Cancer Registry diagnosed in 1991–2010 (n = 2449) were examined.
Results
The use of breast conserving surgery (BCS) went from 17% to 67% in 1991–2010 and administration of radiotherapy after BCS increased to 89%. Axillary lymph node dissection decreased to almost 0%, while sentinel node biopsy was performed in 65% of patients in 2010. The proportion who underwent BCS varied between hospitals from 49% to 80%; the proportion without axillary staging ranged from 21% to 60%. Patients with screen-detected DCIS were more likely to receive BCS.
Conclusion
There was considerable variation in the use of BCS, radiotherapy, and axillary staging of DCIS over time and between hospitals. Patients with DCIS were more likely to be treated with BCS if their disease was detected by screening.
Original languageEnglish
Pages (from-to)63-68
JournalThe breast: Official journal of the European Society of Mastology
Volume23
Issue number1
DOIs
Publication statusPublished - Feb 2014

Keywords

  • DCIS
  • Treatment
  • Axillary staging
  • Variation
  • Screening

Cite this

@article{79cfd5aea5c04c6f95ee6f25873532a3,
title = "Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands",
abstract = "BackgroundTo examine variation in time and place in axillary staging and treatment of patients with ductal carcinoma in situ (DCIS) of the breast.MethodsTrends in patients with DCIS recorded in the Eindhoven Cancer Registry diagnosed in 1991–2010 (n = 2449) were examined.ResultsThe use of breast conserving surgery (BCS) went from 17{\%} to 67{\%} in 1991–2010 and administration of radiotherapy after BCS increased to 89{\%}. Axillary lymph node dissection decreased to almost 0{\%}, while sentinel node biopsy was performed in 65{\%} of patients in 2010. The proportion who underwent BCS varied between hospitals from 49{\%} to 80{\%}; the proportion without axillary staging ranged from 21{\%} to 60{\%}. Patients with screen-detected DCIS were more likely to receive BCS.ConclusionThere was considerable variation in the use of BCS, radiotherapy, and axillary staging of DCIS over time and between hospitals. Patients with DCIS were more likely to be treated with BCS if their disease was detected by screening.",
keywords = "DCIS, Treatment, Axillary staging, Variation, Screening",
author = "{van Steenbergen}, {L. N.} and Voogd, {A. C.} and Roukema, {J. A.} and Louwman, {W. J.} and Duijm, {L. E. M.} and Coebergh, {J. W. W.} and {van de Poll-Franse}, L.",
year = "2014",
month = "2",
doi = "10.1016/j.breast.2013.11.001",
language = "English",
volume = "23",
pages = "63--68",
journal = "The Breast",
issn = "0960-9776",
publisher = "Churchill Livingstone",
number = "1",

}

Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands. / van Steenbergen, L. N.; Voogd, A. C.; Roukema, J. A.; Louwman, W. J.; Duijm, L. E. M.; Coebergh, J. W. W.; van de Poll-Franse, L.

In: The breast: Official journal of the European Society of Mastology, Vol. 23, No. 1, 02.2014, p. 63-68.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands

AU - van Steenbergen, L. N.

AU - Voogd, A. C.

AU - Roukema, J. A.

AU - Louwman, W. J.

AU - Duijm, L. E. M.

AU - Coebergh, J. W. W.

AU - van de Poll-Franse, L.

PY - 2014/2

Y1 - 2014/2

N2 - BackgroundTo examine variation in time and place in axillary staging and treatment of patients with ductal carcinoma in situ (DCIS) of the breast.MethodsTrends in patients with DCIS recorded in the Eindhoven Cancer Registry diagnosed in 1991–2010 (n = 2449) were examined.ResultsThe use of breast conserving surgery (BCS) went from 17% to 67% in 1991–2010 and administration of radiotherapy after BCS increased to 89%. Axillary lymph node dissection decreased to almost 0%, while sentinel node biopsy was performed in 65% of patients in 2010. The proportion who underwent BCS varied between hospitals from 49% to 80%; the proportion without axillary staging ranged from 21% to 60%. Patients with screen-detected DCIS were more likely to receive BCS.ConclusionThere was considerable variation in the use of BCS, radiotherapy, and axillary staging of DCIS over time and between hospitals. Patients with DCIS were more likely to be treated with BCS if their disease was detected by screening.

AB - BackgroundTo examine variation in time and place in axillary staging and treatment of patients with ductal carcinoma in situ (DCIS) of the breast.MethodsTrends in patients with DCIS recorded in the Eindhoven Cancer Registry diagnosed in 1991–2010 (n = 2449) were examined.ResultsThe use of breast conserving surgery (BCS) went from 17% to 67% in 1991–2010 and administration of radiotherapy after BCS increased to 89%. Axillary lymph node dissection decreased to almost 0%, while sentinel node biopsy was performed in 65% of patients in 2010. The proportion who underwent BCS varied between hospitals from 49% to 80%; the proportion without axillary staging ranged from 21% to 60%. Patients with screen-detected DCIS were more likely to receive BCS.ConclusionThere was considerable variation in the use of BCS, radiotherapy, and axillary staging of DCIS over time and between hospitals. Patients with DCIS were more likely to be treated with BCS if their disease was detected by screening.

KW - DCIS

KW - Treatment

KW - Axillary staging

KW - Variation

KW - Screening

U2 - 10.1016/j.breast.2013.11.001

DO - 10.1016/j.breast.2013.11.001

M3 - Article

VL - 23

SP - 63

EP - 68

JO - The Breast

JF - The Breast

SN - 0960-9776

IS - 1

ER -