Towards Horizon 2020

Challenges and advances for clinical mental health research - outcome of an expert survey

C.M. van der Feltz-Cornelis, Jim van Os, Susanne Knappe, Gunter Schumann, Eduard Vieta, Hans-Ulrich Wittchen, Shon W. Lewis, I. Elfeddali, Kristian Wahlbeck, Donald Linszen, Carla Obradors-Tarrago, Josep Maria Haro

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background:
The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental health research and health policy in Europe. The aim of this research was to identify the top priorities needed to address the main challenges in clinical research for mental disorders.
Methods:
The research was conducted as an expert survey and expert panel discussion during a scientific workshop.
Results:
Eighty-nine experts in clinical research and representing most European countries participated in this survey. Identified top priorities were the need for new intervention studies, understanding the diagnostic and therapeutic implications of mechanisms of disease, and research in the field of somatic-psychiatric comorbidity. The “subjectivity gap” between basic neuroscience research and clinical reality for patients with mental disorders is considered the main challenge in psychiatric research, suggesting that a shift in research paradigms is required.
Conclusion:
Innovations in clinical mental health research should bridge the gap between mechanisms underlying novel therapeutic interventions and the patient experience of mental disorder and, if present, somatic comorbidity. Clinical mental health research is relatively underfunded and should receive specific attention in Horizon 2020 funding programs.
Original languageEnglish
Pages (from-to)1057-1068
JournalNeuropsychiatric Disease and Treatment
Volume10
DOIs
Publication statusPublished - 2014

Keywords

  • clinical research
  • mental health
  • randomized clinical trials
  • Horizon 2020
  • expert survey
  • challenge
  • research agenda
  • Europe

Cite this

van der Feltz-Cornelis, C.M. ; van Os, Jim ; Knappe, Susanne ; Schumann, Gunter ; Vieta, Eduard ; Wittchen, Hans-Ulrich ; Lewis, Shon W. ; Elfeddali, I. ; Wahlbeck, Kristian ; Linszen, Donald ; Obradors-Tarrago, Carla ; Maria Haro, Josep. / Towards Horizon 2020 : Challenges and advances for clinical mental health research - outcome of an expert survey. In: Neuropsychiatric Disease and Treatment. 2014 ; Vol. 10. pp. 1057-1068.
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abstract = "Background: The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental health research and health policy in Europe. The aim of this research was to identify the top priorities needed to address the main challenges in clinical research for mental disorders.Methods: The research was conducted as an expert survey and expert panel discussion during a scientific workshop.Results: Eighty-nine experts in clinical research and representing most European countries participated in this survey. Identified top priorities were the need for new intervention studies, understanding the diagnostic and therapeutic implications of mechanisms of disease, and research in the field of somatic-psychiatric comorbidity. The “subjectivity gap” between basic neuroscience research and clinical reality for patients with mental disorders is considered the main challenge in psychiatric research, suggesting that a shift in research paradigms is required.Conclusion: Innovations in clinical mental health research should bridge the gap between mechanisms underlying novel therapeutic interventions and the patient experience of mental disorder and, if present, somatic comorbidity. Clinical mental health research is relatively underfunded and should receive specific attention in Horizon 2020 funding programs.",
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author = "{van der Feltz-Cornelis}, C.M. and {van Os}, Jim and Susanne Knappe and Gunter Schumann and Eduard Vieta and Hans-Ulrich Wittchen and Lewis, {Shon W.} and I. Elfeddali and Kristian Wahlbeck and Donald Linszen and Carla Obradors-Tarrago and {Maria Haro}, Josep",
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van der Feltz-Cornelis, CM, van Os, J, Knappe, S, Schumann, G, Vieta, E, Wittchen, H-U, Lewis, SW, Elfeddali, I, Wahlbeck, K, Linszen, D, Obradors-Tarrago, C & Maria Haro, J 2014, 'Towards Horizon 2020: Challenges and advances for clinical mental health research - outcome of an expert survey', Neuropsychiatric Disease and Treatment, vol. 10, pp. 1057-1068. https://doi.org/10.2147/NDT.S59958

Towards Horizon 2020 : Challenges and advances for clinical mental health research - outcome of an expert survey. / van der Feltz-Cornelis, C.M.; van Os, Jim; Knappe, Susanne; Schumann, Gunter; Vieta, Eduard; Wittchen, Hans-Ulrich; Lewis, Shon W.; Elfeddali, I.; Wahlbeck, Kristian; Linszen, Donald; Obradors-Tarrago, Carla; Maria Haro, Josep.

In: Neuropsychiatric Disease and Treatment, Vol. 10, 2014, p. 1057-1068.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Towards Horizon 2020

T2 - Challenges and advances for clinical mental health research - outcome of an expert survey

AU - van der Feltz-Cornelis, C.M.

AU - van Os, Jim

AU - Knappe, Susanne

AU - Schumann, Gunter

AU - Vieta, Eduard

AU - Wittchen, Hans-Ulrich

AU - Lewis, Shon W.

AU - Elfeddali, I.

AU - Wahlbeck, Kristian

AU - Linszen, Donald

AU - Obradors-Tarrago, Carla

AU - Maria Haro, Josep

PY - 2014

Y1 - 2014

N2 - Background: The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental health research and health policy in Europe. The aim of this research was to identify the top priorities needed to address the main challenges in clinical research for mental disorders.Methods: The research was conducted as an expert survey and expert panel discussion during a scientific workshop.Results: Eighty-nine experts in clinical research and representing most European countries participated in this survey. Identified top priorities were the need for new intervention studies, understanding the diagnostic and therapeutic implications of mechanisms of disease, and research in the field of somatic-psychiatric comorbidity. The “subjectivity gap” between basic neuroscience research and clinical reality for patients with mental disorders is considered the main challenge in psychiatric research, suggesting that a shift in research paradigms is required.Conclusion: Innovations in clinical mental health research should bridge the gap between mechanisms underlying novel therapeutic interventions and the patient experience of mental disorder and, if present, somatic comorbidity. Clinical mental health research is relatively underfunded and should receive specific attention in Horizon 2020 funding programs.

AB - Background: The size and increasing burden of disease due to mental disorders in Europe poses substantial challenges to its population and to the health policy of the European Union. This warrants a specific research agenda concerning clinical mental health research as one of the cornerstones of sustainable mental health research and health policy in Europe. The aim of this research was to identify the top priorities needed to address the main challenges in clinical research for mental disorders.Methods: The research was conducted as an expert survey and expert panel discussion during a scientific workshop.Results: Eighty-nine experts in clinical research and representing most European countries participated in this survey. Identified top priorities were the need for new intervention studies, understanding the diagnostic and therapeutic implications of mechanisms of disease, and research in the field of somatic-psychiatric comorbidity. The “subjectivity gap” between basic neuroscience research and clinical reality for patients with mental disorders is considered the main challenge in psychiatric research, suggesting that a shift in research paradigms is required.Conclusion: Innovations in clinical mental health research should bridge the gap between mechanisms underlying novel therapeutic interventions and the patient experience of mental disorder and, if present, somatic comorbidity. Clinical mental health research is relatively underfunded and should receive specific attention in Horizon 2020 funding programs.

KW - clinical research

KW - mental health

KW - randomized clinical trials

KW - Horizon 2020

KW - expert survey

KW - challenge

KW - research agenda

KW - Europe

U2 - 10.2147/NDT.S59958

DO - 10.2147/NDT.S59958

M3 - Article

VL - 10

SP - 1057

EP - 1068

JO - Neuropsychiatric Disease and Treatment

JF - Neuropsychiatric Disease and Treatment

SN - 1176-6328

ER -