Two cases of rickets presenting with poor growth, hypotonia, and respiratory problems

E. Wouters, M. Wojciechowski, E. de Vries

Research output: Contribution to journalArticleScientificpeer-review


Rickets is a rare disease in developed countries. In children, it is a disease which affects growing bone. Depending on the severity, it can present with a wide variety of symptoms. Because it is such a rare disease in developed countries, symptoms suggesting rickets are often not easily recognized. This can cause a delay in diagnosing and treating rickets. Often unnecessary and sometimes invasive investigations are performed. First leading clues to rickets on physical examination are poor growth, especially length, thickening of wrists, bow legs, and craniotabes. At further examination, special attention should be paid to osteopenia and cupping and fraying at the metaphyses on X-rays. Laboratory results suggestive for rickets are elevated alkaline phosphatase and disturbances in calcium and phosphate homeostasis. In this report, we present two cases presenting with poor growth, severe pain, and respiratory problems secondary to calcipenic rickets.
Keywords: Rickets, Failure to thrive, Vitamin D, Osteopenia, Poor growth
Original languageEnglish
Pages (from-to)211-214
JournalActa Clinica Belgica
Publication statusPublished - 2015


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