Vitamin D status and health-related quality of life in patients with Type 2 diabetes

Y.H. Krul-Poel , S. Westra, H.J. Wijland, F. Stam, P. Lips, F. Pouwer, J. Speight, S. Simsek

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Aims
To test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.
Methods
Demographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.
Results
The mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life.
Conclusions
Vitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.
Original languageEnglish
Pages (from-to)300–306
JournalDiabetic Medicine: Journal of the British Diabetic Association
Volume33
Issue number3
DOIs
Publication statusPublished - 2016

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Type 2 Diabetes Mellitus
Serum
Health Surveys
Hypoglycemic Agents
Logistic Models
25-hydroxyvitamin D

Cite this

Krul-Poel , Y. H., Westra, S., Wijland, H. J., Stam, F., Lips, P., Pouwer, F., ... Simsek, S. (2016). Vitamin D status and health-related quality of life in patients with Type 2 diabetes. Diabetic Medicine: Journal of the British Diabetic Association, 33(3), 300–306. https://doi.org/10.1111/dme.12834
Krul-Poel , Y.H. ; Westra, S. ; Wijland, H.J. ; Stam, F. ; Lips, P. ; Pouwer, F. ; Speight, J. ; Simsek, S. / Vitamin D status and health-related quality of life in patients with Type 2 diabetes. In: Diabetic Medicine: Journal of the British Diabetic Association. 2016 ; Vol. 33, No. 3. pp. 300–306.
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title = "Vitamin D status and health-related quality of life in patients with Type 2 diabetes",
abstract = "AimsTo test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.MethodsDemographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.ResultsThe mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7{\%}) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38{\%} of patients. No significant associations were found between vitamin D status and health-related quality of life.ConclusionsVitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.",
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Krul-Poel , YH, Westra, S, Wijland, HJ, Stam, F, Lips, P, Pouwer, F, Speight, J & Simsek, S 2016, 'Vitamin D status and health-related quality of life in patients with Type 2 diabetes', Diabetic Medicine: Journal of the British Diabetic Association, vol. 33, no. 3, pp. 300–306. https://doi.org/10.1111/dme.12834

Vitamin D status and health-related quality of life in patients with Type 2 diabetes. / Krul-Poel , Y.H.; Westra, S.; Wijland, H.J.; Stam, F.; Lips, P.; Pouwer, F.; Speight, J.; Simsek, S.

In: Diabetic Medicine: Journal of the British Diabetic Association, Vol. 33, No. 3, 2016, p. 300–306.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Vitamin D status and health-related quality of life in patients with Type 2 diabetes

AU - Krul-Poel , Y.H.

AU - Westra, S.

AU - Wijland, H.J.

AU - Stam, F.

AU - Lips, P.

AU - Pouwer, F.

AU - Speight, J.

AU - Simsek, S.

PY - 2016

Y1 - 2016

N2 - AimsTo test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.MethodsDemographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.ResultsThe mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life.ConclusionsVitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.

AB - AimsTo test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.MethodsDemographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.ResultsThe mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life.ConclusionsVitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.

U2 - 10.1111/dme.12834

DO - 10.1111/dme.12834

M3 - Article

VL - 33

SP - 300

EP - 306

JO - Diabetic Medicine: Journal of the British Diabetic Association

JF - Diabetic Medicine: Journal of the British Diabetic Association

SN - 0742-3071

IS - 3

ER -