Vitamin D status and health-related quality of life in patients with Type 2 diabetes

Y.H. Krul-Poel , S. Westra, H.J. Wijland, F. Stam, P. Lips, F. Pouwer, J. Speight, S. Simsek

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)

Abstract

Aims
To test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus.
Methods
Demographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders.
Results
The mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life.
Conclusions
Vitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.
Original languageEnglish
Pages (from-to)300–306
JournalDiabetic Medicine: Journal of the British Diabetic Association
Volume33
Issue number3
DOIs
Publication statusPublished - 2016

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